Effect of submucosal and intramuscular dexamethasone on postoperative sequelae after third molar surgery: comparative study

Majid, Omer Waleed; Mahmood, Waseem Khalid

doi:10.1016/j.bjoms.2010.09.021

Cited by 99 publications

(126 citation statements)

References 24 publications

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“…The rate of absorption is highly dependent on the blood flow to the site. Majid and Mahmood [13] in their study concluded that submucosal dexamethasone injection is quite simple, less invasive, painless, convenient for the surgeon and the patient, and offers low-cost solution for the typical discomfort associated with the extraction of impacted lower third molars. These are the advantages of this technique over the intravenous and intramuscular routes of administration.…”

Section: Discussionmentioning

confidence: 99%

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A Single Pre Operative Dose of Sub Mucosal Dexamethasone is Effective in Improving Post Operative Quality of Life in the Surgical Management of Impacted Third Molars: A Comparative Randomised Prospective Study

Saravanan

Kannan

John

et al. 2015

J. Maxillofac. Oral Surg.

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Objective The aim of the study was to observe and compare the effects of dexamethasone on pain, swelling and trismus administered as one dose preoperatively sub mucosal (study group 2) versus intramuscular injection (study group 1) keeping control as those who received no dose of steroid in the management of third molar surgery. Materials and methods The group 2 (20 patients) is the study group in which all the patients had single dose of preoperative sub mucosal dexamethasone of 4 mg/2 ml. The group 1 patients (20 patients) received single dose of preoperative intra muscular dexamethasone of 4 mg/2 ml. The control group (20 patients) did not receive steroid in any form. The post operative pain, swelling and trismus were assessed for all the groups. Results The submucosal dexamethasone group showed marked improvement in the mouth opening in the follow ups than the intra muscular dexamethasone group. In those five cases of bilateral impaction, in study groups 1 and 2, the mouth opening was very much significant when sub mucosal dexamethasone was given. ConclusionThe pre operative use of submucosal dexamethasone effectively reduces the post operative pain, swelling and trismus showing statistically significant results. The number of post operative use of analgesic tablets taken by the patients in the study group 2 were less compared to the study group 1 and the control group showing clinically significant results.

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Section: Discussionmentioning

confidence: 99%

“…The evaluation of facial swelling was performed using two facial measurements as described by Majid [13]: tragusmidline and gonion-lateral canthus using a tape measure. The preoperative sum of the two values (mm) was taken as the baseline for that side.…”

Section: Assessment Of Swellingmentioning

confidence: 99%

A Single Pre Operative Dose of Sub Mucosal Dexamethasone is Effective in Improving Post Operative Quality of Life in the Surgical Management of Impacted Third Molars: A Comparative Randomised Prospective Study

Saravanan

Kannan

John

et al. 2015

J. Maxillofac. Oral Surg.

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“…Recently, TMS has became a routine, a safe office procedure with generally predictable outcomes and relative low cost due to the development of high speed cutting instruments, panoramic radiograph, improved local anaesthesia and advanced surgical techniques. Moreover, the previous studies which investigated efficacy and effectiveness of preoperative submucosal dexamethasone, gave encouraging results compared with controls in reducing the post-operative sequelae of TMS [13][14][15][16]. Due to this the clinician feels easy to inform their patients about TMS.…”

Section: Discussionmentioning

confidence: 97%

“…Many reports support the use of local application of dexamethasone in the setting of TMS [11][12][13][14][15][16]. But those studies demonstrated conflicting results because of the limited number of subjects, different route and dose of corticosteroid administered, use of different surgical techniques and lack of standardized anaesthetic technique (Local or General).…”

Section: Discussionmentioning

confidence: 99%

“…However, method of usage of corticosteroid in literature has varied; most effective agents, site, dose and route have yet to be defined with respect to TMS [9]. Despite the frequent clinical use of dexamethasone, there are a few reports of corticosteroid administered in proximity to surgical site which have shown positive response after TMS [10][11][12][13][14][15][16]. Even though, QOL measures after administration of preoperative single dose submucosal dexamethasone remains poorly investigated.…”

Section: Introductionmentioning

confidence: 99%

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Single-Dose of Submucosal Injection of Dexamethasone Affects the Post Operative Quality of Life After Third Molar Surgery

Deo

2015

J. Maxillofac. Oral Surg.

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Introduction Third molar surgery (TMS) became a routine, safe office procedure with generally predictable outcomes and relative low cost. It affects quality of life (QOL) of patients by causing considerable pain, swelling and trismus; by changing what people eat, their speech in the first few days after surgery. The purpose of the present study was to improve QOL of patient after lower TMS by injecting single dose 8 mg submucosal dexamethasone. Materials and Methods Forty healthy adult subjects of either gender underwent surgical removal of the lower impacted third molar under local anaesthesia and after being randomly assigned to receive either 8 mg dexamethasone submucosal injection or normal saline injection in proximity to surgical site. Statistical Analysis Used Chi-square test, Mann-Whitney U test (Z), t student and unpaired t test, and Fisher extract test were used for calculation of data. Results Facial swelling, trismus showed significant reduction immediate postoperative day in dexamethasone groups. Patient perception postoperative pain on VAS score was not significant. PoSSe statistics, only three out of seven subscales showed a statistically significant difference between groups viz., Eating subscale, Appearance subscale, Sickness subscale but over all improvement in QOL was observed. Conclusions Submucosal dexamethasone effectively reduces postoperative sequelae and improves postoperative QOL after TMS.

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Local interventions for the management of alveolar osteitis (dry socket)

Daly

Sharif

Newton³

et al. 2012

Cochrane Database of Systematic Reviews

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Most tooth extractions are undertaken by dentists for a variety of reasons, however, all but three studies included in the present review included participants undergoing extraction of third molars, most of which were undertaken by oral surgeons. There is some evidence that rinsing with chlorhexidine (0.12% and 0.2%) or placing chlorhexidine gel (0.2%) in the sockets of extracted teeth, provides a benefit in preventing dry socket. There was insufficient evidence to determine the effects of the other 10 preventative interventions each evaluated in single studies. There was insufficient evidence to determine the effects of any of the interventions to treat dry socket. The present review found some evidence for the association of minor adverse reactions with use of 0.12%, 0.2% and 2% chlorhexidine mouthrinses, though most studies were not designed to detect the presence of hypersensitivity reactions to mouthwash as part of the study protocol. No adverse events were reported in relation to the use of 0.2% chlorhexidine gel placed directly into a socket (though previous allergy to chlorhexidine was an exclusion criterion in these trials). In view of recent reports in the UK of two cases of serious adverse events associated with irrigation of dry socket with chlorhexidine mouthrinse, it is recommended that all members of the dental team prescribing chlorhexidine products are aware of the potential for both minor and serious adverse side effects.

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Effect of submucosal and intramuscular dexamethasone on postoperative sequelae after third molar surgery: comparative study

Cited by 99 publications

References 24 publications

A Single Pre Operative Dose of Sub Mucosal Dexamethasone is Effective in Improving Post Operative Quality of Life in the Surgical Management of Impacted Third Molars: A Comparative Randomised Prospective Study

A Single Pre Operative Dose of Sub Mucosal Dexamethasone is Effective in Improving Post Operative Quality of Life in the Surgical Management of Impacted Third Molars: A Comparative Randomised Prospective Study

Single-Dose of Submucosal Injection of Dexamethasone Affects the Post Operative Quality of Life After Third Molar Surgery

Local interventions for the management of alveolar osteitis (dry socket)

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