Purpose of the study. This study was to evaluate the use of buccal fat pad as an interpositioning material in surgical management of oral sub mucous fibrosis. Materials and methods. A series of 8 cases with proven oral sub mucous fibrosis, with mouth opening less than 20 mm, involving the buccal mucosa were treated surgically in the Department of Oral and Maxillofacial Surgery, College of Dental Surgery, Saveetha University, Chennai. Pedicled buccal fat pad was used as an interpositioning material to cover the raw areas in the oral cavity after incision and release of fibrous bands. Results. In 8 patients, the range of pre operative mouth opening was 3–18 mm (mean 14 mm). As the result of the successful surgical procedure, the size of the intra operative mouth opening was ranged from 25–38 mm (mean 33.25 mm). The patients were discharged 5–7 days after the operation. The range of the mouth opening at this time was 25–36 mm (mean 30.63 mm). The results were evaluated using student's t test and found to be statistically significant. The pedicled grafts took up uneventfull.

Objective The aim of the study was to observe and compare the effects of dexamethasone on pain, swelling and trismus administered as one dose preoperatively sub mucosal (study group 2) versus intramuscular injection (study group 1) keeping control as those who received no dose of steroid in the management of third molar surgery. Materials and methods The group 2 (20 patients) is the study group in which all the patients had single dose of preoperative sub mucosal dexamethasone of 4 mg/2 ml. The group 1 patients (20 patients) received single dose of preoperative intra muscular dexamethasone of 4 mg/2 ml. The control group (20 patients) did not receive steroid in any form. The post operative pain, swelling and trismus were assessed for all the groups. Results The submucosal dexamethasone group showed marked improvement in the mouth opening in the follow ups than the intra muscular dexamethasone group. In those five cases of bilateral impaction, in study groups 1 and 2, the mouth opening was very much significant when sub mucosal dexamethasone was given. ConclusionThe pre operative use of submucosal dexamethasone effectively reduces the post operative pain, swelling and trismus showing statistically significant results. The number of post operative use of analgesic tablets taken by the patients in the study group 2 were less compared to the study group 1 and the control group showing clinically significant results.

Oral sub mucous fibrosis is an insidious chronic disease affecting any part of the oral cavity. Worldwide estimates of oral sub mucous fibrosis indicate that 2.5 million people are affected, with most cases concentrated in the Indian subcontinent, especially eastern and southern India. Oral sub mucous fibrosis has a propensity for malignant transformation. The association of betel quid chewing, oral sub mucous fibrosis, and oral squamous cell carcinoma is quite profound, especially in Taiwan and the Indian subcontinent where up to 80% of oral squamous cell carcinoma is associated with the habit. Epidemiological studies have shown that the rate of malignant transformation ranges from 3 to 19%.

Background: Surgical site infections (SSI) are one of the most common postoperative complications leading to increased morbidity which also an important factor of increased hospital stays and increased healthcare cost. The use of prophylactic antibiotics may benefit the patients in preventing the surgical site infection. Aim of the study was to study the single dose prophylactic antibiotic use in preventing surgical site infection in elective surgery.Methods: Patients were included from the list of elective surgery. Patient with comorbid was excluded. The patient was handled as per NICE guideline for prevention of surgical site infection and treatment 2017. Prophylactic antibiotic injection cefuroxime 1500mg administered intravenously 30 minutes before surgery, at the site of the incision.Results: In 110 patients included in the study, 46% of patients were in 35 to 45 years, male were higher in number. 20% of patients underwent hernioplasty followed by cholecystectomy 18.3%. 9% of SSI was recorded in this study. 4 cases in cholecystectomy, 3 cases in hernioplasty, each 1 case in appendicectomy, Hydrocele and ventral hernia mesh repair. The most common bacteria isolated from the samples were Staphylococcus aureus.Conclusions: In uncomplicated surgeries, single dose antibiotics before 30 minutes of surgery may benefit in preventing SSI.

How to cite this article: K. Saravanan, A. Muthukumar. Prophylaxis pre-operative single dose antibiotic versus conventional antibiotic therapy in lichtenstein tension free mesh repair. International Journal of Contemporary Medicine Surgery and Radiology. 2019;4(2):B170-B172. MATERIAL AND METHODS This prospective comparative study was conducted department of General Surgery, Government Theni Medical College Hospital in elective Lichtenstein tension-free mesh A B S T R A C T Introduction: Surgical antibiotic prophylaxis (SAP) refers to the utilization of antibiotics for the prevention of surgical site infections (SSIs). SSIs impact on both the patient and health care system through increased mortality and morbidity, prolonged hospital admission, reduced the quality of life and additional financial costs for ongoing inpatient and outpatient treatment. Aim: To study the effect of single-dose antibiotic prophylaxis given 30 minutes prior to surgery with conventional antibiotic therapy. Material and Methods: Total of 50 patients were randomized to 25 each group. All patients in the study group undergoing surgery were given 400 mg parenteral ciprofloxacin 30 min prior to surgery. In the control group, the patients were given 2 days parenteral ciprofloxacin 400 mg twice a day and the next 5 days the same antibiotics were given in oral route, after surgery. The outcome in terms of duration of surgery, surgical site infection, cost and antibiotic side effects were then compared. Results: Out of 50 patients, the incidence of postoperative infection 10% (5 patients), 3 cases in the control group and 2 patients prophylactic antibiotic group. No change in the management protocol was done. None developed antibiotic side effects in the study group. Control group patients developed study effects of nausea, vomiting and diarrhoea. Conclusion: Prophylactic single-dose antibiotic is effective in preventing surgical site infection and is cost-effective in patients undergoing Lichtenstein tension-free mesh repair.