Effect of substrate patterning on hydroxyapatite sol–gel thin film growth

Structural and Antimicrobial Evaluation of Silver Doped Hydroxyapatite-Polydimethylsiloxane Thin Layers

“…The most studied element for its excellent antimicrobial properties is silver. It has been extensively used as an antimicrobial agent in many medical devices such as wound dressings, cardiac prostheses, bone cements, catheters, and orthopedic fixation pins [13][14][15]. Although HAp is a bioactive material, an approach to improve the osseointegration, the mechanical properties, and the antimicrobial activity is to chemically modify HAp by doping it with low levels of beneficial elements.…”

Calcium Phosphate Nanocoatings and Nanocomposites, Part I: Recent Developments and Advancements in Tissue Engineering and Bioimaging

“…The same sol-gel based nanocoatings technique can also be used -with an appropriate chemistry -to metallic and ceramic implants ( Figure 3) using a range of biocompatible ceramic oxide materials (Al 2 O 3 , partially stabilized zirconia, TiO 2 , Ta 2 O 5 and SiO 2 ) to increase strength, In addition to using calcium alkoxide, researchers have also synthesized calcium phosphate nanocoatings with thicknesses ranging from 20 to 1000 nm on a number of substrates using calcium acetate [11] and calcium nitrate [12][13][14] as the calcium precursors ( Figure 4). More recently, Mudenda et al [14] studied the microstructure evolution of calcium phosphate nanocoatings approximately 400 nm thick on wet and dry-etched micro-patterned titanium substrates. They observed the nanocoatings on wet-etched substrates contained larger calcium phosphate grains than the nanocoatings on dry-etched substrates.…”