Effect of sulfhydryl reagents on peroxidation in microsomes

Utley, Henry G.; Bernheim, Frederick; Hochstein, Paul

doi:10.1016/0003-9861(67)90273-1

Cited by 461 publications

(209 citation statements)

References 4 publications

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“…Homogenate was used for the estimation of amount of malondialdehyde formed per 30 minutes during lipid peroxidation by the method of Utely et al (16). Nucleic acids were isolated by usingmethod of Searchy and Macinnis (17).…”

Section: Biochemical Assaysmentioning

confidence: 99%

Effect of methyl mercury induced free radical stress on nucleic acids and protein: Implications on cognitive and motor functions

Zahir

Rizvi

Haq

et al. 2006

Indian J Clin Biochem

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Section: Biochemical Assaysmentioning

confidence: 99%

Effect of methyl mercury induced free radical stress on nucleic acids and protein: Implications on cognitive and motor functions

Zahir

Rizvi

Haq

et al. 2006

Indian J Clin Biochem

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“…Color formation at 535 nm was determined in the supernatant. The molar extinction coefficient of malonaldehyde (MDA) derivative at this wavelength (1.56 x 10 5) was used to determine the malonaldehyde equivalent produced (Utley et al, 1967). This procedure determines the in vitro levels of peroxides rather than the rate of peroxidation in vitro, and is more sensitive to perturbation by toxic agents than the latter procedure (Mihara et al, 1980).…”

Section: Assay For Lipid Peroxidationmentioning

confidence: 99%

Toluene-induced oxidative stress in several brain regions and other organs

Mattia

Ali

Bondy

1993

Molecular and Chemical Neuropathology

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“…Lipid peroxide level in 10% RBC hemolysate was determined as per Placer et al (1966) and was expressed as nmol malondialdehyde (MDA)/mg of hemoglobin (Hb) using 1.56×10 5 as extinction coefficient (Utley et al, 1967). For the preparation of 10% RBC hemolysate, blood samples were centrifuged at 2000 rpm for 10 min and supernatant plasma were separated out.…”

Section: Biochemical Assaymentioning

confidence: 99%

Bromadiolone Induced Oxidative Stress and Cytological Damage in Layer Birds

Sodhi

Brar

Banga

2017

IJAVST

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This study was undertaken to evaluate the oxidative stress induced by bromadiolone toxicity in layers. Birds were divided into two groups. Control group (I) received bromadiolone free feed and group (II) was exposed to bromadiolone (5 mg/kg feed) for seven weeks. Blood samples and organs were collected at the end of the experiment. Bromadiolone exposure resulted in significant rise in lipid peroxidation (LPO) levels in erythrocyte and liver. In addition decreased (P<0.05) level of reduced glutathione (GSH), superoxide dismutase (SOD), and catalase (CAT) activities were observed in erythrocyte and liver. Histopathological results revealed mild to severe type of necrosis and degenerative changes in heart and liver of bromadiolone intoxicated animals. In addition histopathological findings of tissues ovary, liver, heart and pancreas also showed generalized haemorrhage. It is therefore concluded that feeding of bromadiolone admixed feed lead to depletion of Vitamin K causing multifocal haemorrhages and oxidative stress and cellular damage in different tissues.

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Effect of sulfhydryl reagents on peroxidation in microsomes

Cited by 461 publications

References 4 publications

Effect of methyl mercury induced free radical stress on nucleic acids and protein: Implications on cognitive and motor functions

Effect of methyl mercury induced free radical stress on nucleic acids and protein: Implications on cognitive and motor functions

Toluene-induced oxidative stress in several brain regions and other organs

Bromadiolone Induced Oxidative Stress and Cytological Damage in Layer Birds

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