Effect of TGFβ1 and nAG on Astrocyte Cultures: A Study of Astrocyte Proliferation and the Expression of GFAP, CSPG4, S100B and IL-6

In 2001, the concept of the neurovascular unit was introduced at the Stroke Progress Review Group meeting. The neurovascular unit is an important element of the health and disease status of blood vessels and nerves in the central nervous system. Since then, the neurovascular unit has attracted increasing interest from research teams, who have contributed greatly to the prevention, treatment, and prognosis of stroke and neurodegenerative diseases. However, additional research is needed to establish an efficient, low-cost, and low-energy in vitro model of the neurovascular unit, as well as enable noninvasive observation of neurovascular units in vivo and in vitro . In this review, we first summarize the composition of neurovascular units, then investigate the efficacy of different types of stem cells and cell culture methods in the construction of neurovascular unit models, and finally assess the progress of imaging methods used to observe neurovascular units in recent years and their positive role in the monitoring and investigation of the mechanisms of a variety of central nervous system diseases.

show abstract

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

customersupport@researchsolutions.com

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Made with 💙 for researchers

Part of the Research Solutions Family.

Effect of TGFβ1 and nAG on Astrocyte Cultures: A Study of Astrocyte Proliferation and the Expression of GFAP, CSPG4, S100B and IL-6

Cited by 2 publications

References 0 publications

RETRACTED: Curcumin inhibits proliferation and soluble collagen synthesis of NIH/3T3 cell line by modulation of miR-29a and via ERK1/2 and β-catenin pathways

RETRACTED: Curcumin inhibits proliferation and soluble collagen synthesis of NIH/3T3 cell line by modulation of miR-29a and via ERK1/2 and β-catenin pathways

Construction and imaging of a neurovascular unit model

Contact Info

Product

Resources

About