Effect of the Acquired Pellicle and of Dental Plaque on the Implantation of Streptococcus mutans on Tooth Surfaces in Man

Ruangsri, Porjai; Ørstavik, Dag

doi:10.1159/000260269

Cited by 37 publications

(18 citation statements)

References 18 publications

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“…The kind and amount of bound salivary components in turn may influence the colonisation of these surfaces by different micro-organisms, for instance by Streptococcus mutans on teeth [31,36,38,45], which is a known prerequisite for caries, or by Candida albicans on mucosal surfaces, which is responsible for denture stomatitis [10]. Colonisation and growth of these micro-organisms also takes place on artificial surfaces such as dental materials, but with somewhat different properties [10,30], from where they may spread to the teeth or mucosal areas.…”

Section: Introductionmentioning

confidence: 99%

Quantitative determination of salivary components in the pellicle on PMMA denture base material

Göcke¹,

Gerath

Schwanewede

2002

Clinical Oral Investigations

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The formation of a salivary pellicle is a protective mechanism of the body for all surfaces in the oral cavity. The nature of the substrate may influence the composition of the pellicle. The aim of this study was to investigate the quantitative composition and individual variation of the salivary pellicle formed on denture base material (PMMA). Cylindrical specimens of PMMA were carried in the mouth and then desorbed with a 0.5-M sodium chloride solution. The solution was analysed for total protein, alpha-amylase, total proteases, protease inhibitors, secretory immunoglobulin A, immunoglobulin G, peroxidases, thiocyanate, lysozyme, and calcium content. All investigated salivary components could be found unequivocally in the desorption solution, indicating that a salivary pellicle had formed on the surface of the PMMA. Large coefficients of variation indicate large individual variations in the adsorbed amounts. The data also point to large intraindividual variations for the bound salivary components. Only the protease inhibitors revealed a strong positive correlation of the bound activity to the salivary activity. It is hypothesised that differences in the bound amounts of antimicrobial components might influence the microbial colonisation of denture bases and that protease inhibitors could be meaningful for the spread of the yeast Candida albicans from denture base material to the oral mucosa and thus might be an explanation for different susceptibility to denture base stomatitis.

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Section: Introductionmentioning

confidence: 99%

Quantitative determination of salivary components in the pellicle on PMMA denture base material

Göcke¹,

Gerath

Schwanewede

2002

Clinical Oral Investigations

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“…Liljemark and Schauer [1977] demonstrated increased ad sorption of S. sanguis and S. mitis cells to saliva-coated apatite, when compared to ad sorption to untreated apatite, although the adsorption of 5. mutans cells was unaffect ed. Ruangsri and Orstavik [1977] reported that, in vivo, the acquired pellicle actually impaired implantation on newly cleaned tooth surfaces. Clark et al [1978] showed that saliva pretreatment increased the affini ty of hydroxyapatite beads for cells of S. mutans even though the total number of ad sorption sites on the beads was considerably reduced.…”

Section: Discussionmentioning

confidence: 99%

Fragility of Salivary Aggregates of Streptococcus mutans

Kashket¹,

Liberman²

1979

Caries Res

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The aggregates produced by mixing saliva with cells of several strains of Streptococcus mutans, unlike those of Streptococcus mitis and Streptococcus sanguis, are extremely fragile. Aggregation of S. mutans cells can be followed spectrophotometrically but cannot be detected, after mechanical agitation, in an electronic particle counter. The salivary aggregating factor for a strain of S. mutans is shown to be different from those for S.mitis and S. sanguis. These findings are consistent with the poor adhesion of cells of S. mutans to saliva-treated hydroxyapatite and the relatively low incidence of S. mutans in dental plaque.

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“…The effector strain was also designed to produce elevated levels of a novel peptide antibiotic, mutacin1140, giving it a strong advantage over competing strains of S. mutans. Previous attempts to re-colonize the oral flora with less pathogenic bacteria had failed due to the resistance of the resident S. mutans strains to the colonizers [27,30,41,50].…”

Section: Introductionmentioning

confidence: 99%

A Review of Probiotic Therapy in Preventive Dental Practice

Cannon

2011

Probiotics & Antimicro. Prot.

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Probiotics have been widely publicized in the general press and the consumer media. Knowledge of the existence of "probiotics" is commonplace, and the effectiveness of probiotic therapy has been well reported in the medical literature. However, even though most published dental studies have reported positive results, the dental profession has not yet accepted the use of probiotic therapy as an adjunct for preventive dental care. This review article discusses published and current research into the applications of probiotics along with diagnostic testing of the oral biofilm. Probiotic therapy appears to be generally safe and effective in modifying with beneficial bacteria the oral biofilm and thereby reducing the effects of pathogenic oral bacteria. In this review, some examples of current oral probiotic research are discussed along with reference to the potential application of diagnostic testing of the oral biofilm for the presence of oral pathogens as a precursor to initiation of specific probiotic therapy. Dental professionals should be actively investigating this potentially very useful therapeutic measure for the benefit of their patients.

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Effect of the Acquired Pellicle and of Dental Plaque on the Implantation of Streptococcus mutans on Tooth Surfaces in Man

Cited by 37 publications

References 18 publications

Quantitative determination of salivary components in the pellicle on PMMA denture base material

Quantitative determination of salivary components in the pellicle on PMMA denture base material

Fragility of Salivary Aggregates of Streptococcus mutans

A Review of Probiotic Therapy in Preventive Dental Practice

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