Effect of the addition of chlorhexidine and miswak extract on the clinical performance and antibacterial properties of conventional glass ionomer: an <i>in vivo</i> study

Kabil, Noha; Badran, Amira; Wassel, Mariem

doi:10.1111/ipd.12273

Cited by 31 publications

(31 citation statements)

References 32 publications

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“…A recent study showed that the addition of 0.5% CHX to GIC improved antibacterial properties compared to conventional GIC, without affecting the clinical performance of class I restorations in young permanent molars until the 3-month follow-up. However, in contrast to our results, after 9 months the restoration success with GIC containing CHX (60%) was lower than the control group (85%) 14 . Differences of age, type of dentition and restorative material used could explain the disparities found in the studies.…”

Section: Discussioncontrasting

confidence: 99%

In vitro and in vivo evaluations of glass-ionomer cement containing chlorhexidine for Atraumatic Restorative Treatment

et al. 2017

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Objectives:Addition of chlorhexidine has enhanced the antimicrobial effect of glass ionomer cement (GIC) indicated to Atraumatic Restorative Treatment (ART); however, the impact of this mixture on the properties of these materials and on the longevity of restorations must be investigated. The aim of this study was to evaluate the effects of incorporating chlorhexidine (CHX) in the in vitro biological and chemical-mechanical properties of GIC and in vivo clinical/ microbiological follow-up of the ART with GIC containing or not CHX.Material and Methods:For in vitro studies, groups were divided into GIC, GIC with 1.25% CHX, and GIC with 2.5% CHX. Antimicrobial activity of GIC was analyzed using agar diffusion and anti-biofilm assays. Cytotoxic effects, compressive tensile strength, microhardness and fluoride (F) release were also evaluated. A randomized controlled trial was conducted on 36 children that received ART either with GIC or GIC with CHX. Saliva and biofilm were collected for mutans streptococci (MS) counts and the survival rate of restorations was checked after 7 days, 3 months and one year after ART. ANOVA/Tukey or Kruskal-Wallis/ Mann-Whitney tests were performed for in vitro tests and in vivo microbiological analysis. The Kaplan-Meier method and Log rank tests were applied to estimate survival percentages of restorations (p<0.05).Results:Incorporation of 1.25% and 2.5% CHX improved the antimicrobial/anti-biofilm activity of GIC, without affecting F release and mechanical characteristics, but 2.5% CHX was cytotoxic. Survival rate of restorations using GIC with 1.25% CHX was similar to GIC. A significant reduction of MS levels was observed for KM+CHX group in children saliva and biofilm 7 days after treatment.Conclusions:The incorporation of 1.25% CHX increased the in vitro antimicrobial activity, without changing chemical-mechanical properties of GIC and odontoblast-like cell viability. This combination improved the in vivo short-term microbiological effect without affecting clinical performance of ART restorations.

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Section: Discussioncontrasting

confidence: 99%

In vitro and in vivo evaluations of glass-ionomer cement containing chlorhexidine for Atraumatic Restorative Treatment

et al. 2017

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“…Glass-ionomer cements (GICs) have important properties for applications as restorative materials, such as the ability to chemically adhere to the enamel and dentin, low thermal expansion coefficient, and biocompatibility [6][7][8]. On the other hand, these materials show disadvantages like low wear and fracture resistance, making them unsuitable for applications in posterior-tooth restorations [9][10][11]. Another limitation of GIC includes high microleakage in sandwich restorations where phosphoric acid etching of GIC prior to the placement of composite resin does not improve the sealing ability of sandwich restorations [12].…”

Section: Introductionmentioning

confidence: 99%

Properties of zirconia-containing glass-ionomer cement

et al. 2019

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Glass-ionomer cements (GICs) are used as restorative dental materials due to their capacity to chemically adhere to enamel and dentin, low thermal expansion coefficient, and compatibility with dental structures. However, these materials have low resistance to wear and fracture. In this work, zirconia-reinforced GICs were prepared to evaluate the influence of particle size as well as ZrO2 content on their properties. All evaluated composites presented compressive strength values above the pure GIC strength. The highest compressive strength values were obtained with the addition of 8.5 wt% ZrO2. The average roughness obtained was not significantly changed compared to commercial GIC and the lowest value was for the composite with 10 wt% ZrO2 (50 mesh). In the microhardness test, the highest values were obtained with the addition of 8.5 wt% of ZrO2. Therefore, the results indicated that the addition of ZrO2 to GIC is an effective alternative to improve the quality of dental restorations.

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“…A odontologia minimamente invasiva tem enfatizado a preservação máxima do tecido durante manejo de lesões profundas de cárie dentinária. A remoção seletiva da dentina é recomendada com o intuito de preservar ao máximo a estrutura dentária e evitar uma possível exposição pulpar (Kabil et al, 2017;Ornellas et al, 2018). Nesse sentindo, a completa vedação da cavidade é capaz de promover a redução bacteriana após um determinado período de tempo e viabilizar a remineralização na dentina afetada dependendo do material utilizado, desempenhando, assim, um papel relevante no sucesso do tratamento (Melo et al, 2015;Pinheiro et al, 2018;Ornellas et al, 2018).…”

Section: Lesões De Cárie Em Dentinaunclassified

“…A selagem ideal da cavidade aumenta a longevidade das restaurações dentárias ao cortar o suprimento de nutrientes bacterianos, impedindo assim a progressão da lesão cariosa. Entretanto, recorrência de cárie e sensibilidade pósoperatória podem ocorrer devido à presença de microrganismos viáveis após o preparo cavitário (Pinheiro et al, 2018;Kabil et al, 2017;Melo et al, 2015).…”

Section: Lesões De Cárie Em Dentinaunclassified

Eficácia do uso de lasers ou clorexidina na redução microbiana em lesões de cárie produzidas artificialmente

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Effect of the addition of chlorhexidine and miswak extract on the clinical performance and antibacterial properties of conventional glass ionomer: an in vivo study

Cited by 31 publications

References 32 publications

In vitro and in vivo evaluations of glass-ionomer cement containing chlorhexidine for Atraumatic Restorative Treatment

In vitro and in vivo evaluations of glass-ionomer cement containing chlorhexidine for Atraumatic Restorative Treatment

Properties of zirconia-containing glass-ionomer cement

Eficácia do uso de lasers ou clorexidina na redução microbiana em lesões de cárie produzidas artificialmente

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