Effect of the aqueous root extract of Curcuma longa L. (turmeric) against thermally oxidized oil-induced hematological, biochemical and histopathological alterations

Abdallah, Amany A. M.; El-Deen, Nasr A.M. Nasr; El-Aziz, Heba I. Abd; Neamat‐Allah, Ahmed N. F.

doi:10.1007/s00580-020-03108-w

Cited by 23 publications

(7 citation statements)

References 40 publications

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“…Time of sampling of the healthy group was performed at the full term of pregnancy, where in Ut group was performed at presentation before correction, and in Utc group was performed 5 days after the manual correction. The blood samples were divided into two portions: the first portion was 2 ml collected into EDTA tubes for hematological examinations within 2 h (Hashem et al 2018b;Neamat-Allah et al 2019a, b), where the second was 10 ml of blood collected into a plain tubes and allowed to clot before separation of the serum by centrifugation at 3000 rpm for 20 min (Abdallah et al 2020a, Abdallah et al 2020b, Neamat-Allah et al 2020a). The serum was then stored at − 20°until biochemical analysis (Badr et al 2011;El-Murr et al 2019;Salem et al 2011;Hashem et al 2020;Mahmoud et al 2020;Neamat-Allah et al 2020b) at the clinical pathology lab of Zagazig University.…”

Section: Blood Samplingmentioning

confidence: 99%

Influence of uterine torsion in water buffaloes (Bubalus bubalis) with insights into the hematological and biochemical prognostic values regarding to manual correction

Mahmoud

Essawi

Neamat‐Allah

2020

Trop Anim Health Prod

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Bovine uterine torsion refers to the rotation of the gravid uterus around its longitudinal axis. It is the dominant cause of dystocia in buffaloes. A total of two hundred and seventeen dystocia's Egyptian buffaloes were examined, and another twenty were apparently normal at the full term (healthy pregnant group). From the dystocia's buffaloes, twenty-three percentage (n = 50) was uterine torsion after gynecology inspection at presentation (Ut group) and 5 days after the manual correction (Utc group). The buffaloes with uterine torsion exhibited loss of appetite, constipation, colic, and straining. The incidence of torsion was mostly at first parity that accounting for 50% of cases. Regarding to the pregnancy stage, torsion mostly occurred at full term, where it primarily occurred in buffaloes at 3 years of age. Right-sided torsion ensued in 90% of all cases. The survival rate of the pregnant buffaloes was 90% (45 buffaloes), and 10% (5 buffaloes) was directed to the culling. Regarding to the fetal survival outcome, 30% of fetuses was survived where the other 70% was died. The hematological results denoted leucocytosis in Ut and Utc groups that attributed to neutrophilia, monocytosis, and eosinophilia. Biochemical assessments were denoted an augments in the levels of serum AST, LDH, CPK, creatinine, blood urea nitrogen, progesterone, cortisol, MDA, NO, TAC, blood lactate (bLac), TNF-α, and IL-6. Where there were a non significant fluctuations in the ALT, GGT, calcium, and phosphorus levels in the torsion cases. The significant declines in 17-β-oestradiol, total proteins, albumin, magnesium, and GSH levels in the dams suffering from Ut were observed. The robust elevations in AST (156 ± 3.47) and bLac (16.12 ± 0.18) with severe hypomagnesaemia (2.69 ± 0.15) were evident in 10% of the torsion cases that directed to the culling. This can conclude that robust elevations in AST and bLac with severe hypomagnesaemia are factors denoting a poor prognosis for uterine torsion in the buffaloes.

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Section: Blood Samplingmentioning

confidence: 99%

Influence of uterine torsion in water buffaloes (Bubalus bubalis) with insights into the hematological and biochemical prognostic values regarding to manual correction

Mahmoud

Essawi

Neamat‐Allah

2020

Trop Anim Health Prod

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“…After postmortem examination, tissue samples from the spleen, liver, and lungs were quickly excised and preserved in 10% buffered formalin; the preserved tissues were quickly processed for histopathological examination. All standard protocols for histopathological examination, including fixation, washing, dehydration, clearing, embedding, block preparation, sectioning, and mounting, were adopted ( Abdallah et al., 2020 ).…”

Section: Methodsmentioning

confidence: 99%

Response of lymphatic tissues to natural feed additives, curcumin (Curcuma longa) and black cumin seeds (Nigella sativa), in broilers against Pasteurella multocida

Raheem

Yin

et al. 2021

Poultry Science

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The antibiotic residues and pathogenic resistance against the drug are very common in poultry because of antibiotics used in their feed. It is necessary to use natural feed additives as effective alternatives instead of a synthetic antibiotic. This study aimed to investigate the immune response of Nigella sativa and Curcuma longa in broilers under biological stress against Pasteurella multocida . The total 100, one-day-old chicks were divided into 5 groups. Groups 1 and 2 served as control negative and control positive. Both control groups were receiving simple diet without any natural feed additives, but the infection was given in group 2 at day 28 with the dose of 5.14 × 10 7 CFU by IV. Groups 3A and 3B were offered 2% seed powder of Nigella sativ a, groups 4A and 4B were offered C. longa 1% in powdered form, and group 5A and 5B were offered both C. longa 1% and N. sativa 2% in the feed from day 1 and groups 3B, 4B, and 5B were challenged with P. multocida . The haemagglutination inhibition titter against Newcastle Disease virus (NDV), feed conversion ratio, mortality, gross, and histopathology were studied. The results of this study revealed that hemagglutination inhibition titers against NDV were highly significant ( P < 0.05) in treated groups, highest titers (3A, 6.8; 3B, 6.4; and 5A, 7.2) were obtained from treated Groups. The feed conversion ratio of N. sativa + C. longa treated groups (5A, 1.57, and 3A, 1.76) were higher than that of other nontreated groups. The gross and histopathological changes were much severe in control positive, but fewer changes were seen in treated groups. Therefore, we recommend that natural feed additives, black cumin (N. sativa) and turmeric ( C. longa ), act as an immune enhancer in broilers against P. multocida.

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“…The preserved tissues were quickly processed for histopathological examination. All standard protocols for histopathological examination including fixation, washing, dehydration, clearing, embedding, block preparation, sectioning and Mounting were adopted [56].…”

Section: Histopathologymentioning

confidence: 99%

Response of Lymphatic Tissues to Dietary Supplementation of Nigella Sativa and Curcuma Longa in Broilers Challenged with <em>Pasteurella Multocida</em>

Ma¹,

Jiangang²,

Yin³

et al. 2020

Preprint

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The antibiotic residues and pathogenic resistance against the drug are very common in poultry due to usage of antibiotics in their feed. It is the need of the time to use natural feed additives as effective alternatives instead of synthetic antibiotic. The aim of this study was to investigate the immune response of Nigella sativa and Curcuma longa in broilers under biological stress against Pasteurella multocida. The total 100, one-day old chicks were divided into 5 groups. The Groups 1 and 2 were served as control negative and control positive. Both control groups were receiving simple diet without any natural feed additives but infection was given in Group 2 at day 28 with the dose of 5.14×107 CFU by IV. Groups 3A & 3B were offered 2% seed powder of Nigella sativa, Groups 4A & 4B were offered Curcuma longa 1% in powdered form and Group 5A & 5B were offered both Curcuma longa 1% & Nigella sativa 2% in feed from day 1 and groups 3B, 4B and 5B were challenged with Pasteurella multocida. The Haemagglutination inhibition titter against Newcastle Disease Virus (NDV), feed conversion ratio, mortality, gross and histopathology were studied. The results of this study revealed that haemagglutination inhibition titers against NDV were highly significant (P< 0.05) in treated groups, highest titers (3A 6.8, 3B 6.4 and 5A 7.2) were obtained from treated Group. The feed conversion ratio (FCR) of Nigella sativa + Curcuma longa treated Groups (5A 1.57 and 3A 1.76) were higher as compared to other non-treated groups. The gross and histopathological changes were much severe in control positive, but less changes were seen in treated groups. Therefore, we recommend that natural feed additives; black cumin (Nigella sativa) and turmeric (Curcuma longa) act as immune enhancer in broilers against Pasteurella multocida.

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Effect of the aqueous root extract of Curcuma longa L. (turmeric) against thermally oxidized oil-induced hematological, biochemical and histopathological alterations

Cited by 23 publications

References 40 publications

Influence of uterine torsion in water buffaloes (Bubalus bubalis) with insights into the hematological and biochemical prognostic values regarding to manual correction

Influence of uterine torsion in water buffaloes (Bubalus bubalis) with insights into the hematological and biochemical prognostic values regarding to manual correction

Response of lymphatic tissues to natural feed additives, curcumin (Curcuma longa) and black cumin seeds (Nigella sativa), in broilers against Pasteurella multocida

Response of Lymphatic Tissues to Dietary Supplementation of Nigella Sativa and Curcuma Longa in Broilers Challenged with <em>Pasteurella Multocida</em>

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