Effect of the detraining status on high-fat diet induced fat accumulation in the adipose tissue and liver in female rats

Yasari, Siham; Dufresne, Élise; Prud’homme, Denis; Lavoie, Jean-Marc

doi:10.1016/j.physbeh.2007.03.012

Cited by 20 publications

(31 citation statements)

References 23 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…What is more important is that, since the brain is a very vulnerable and sensitive organ, the duration and severity of DM might result in serious neurodegenerative diseases such as Alzheimer's disease and Parkinson's disease [10,70,102] . The HPA axis regulates responses to various stress factors, digestion, immune response, mood and emotions, sexuality and energy expenditure/storage [11,59,104,[132][133][134] . In addition, since the HPA axis is also connected with the autonomic nervous system [135,136] , it is very important when the response of the HPA axis regulation [137] .…”

Section: Dm and Central Nervous Systemmentioning

confidence: 99%

“…In addition, an important element in the study of effects of exercise on food preference is sex differences [171,175,179] . Sex differences exist such that female rats tend to prefer carbohydrates over other macronutrients following exercise [134,175] . Unfortunately, there is still no clear evidence on the effect of exercise on macronutrient or carbohydrate selection in different sexes in animal or human studies.…”

Section: Effects Of Exercise On the Brain Of Diabetic Animalsmentioning

confidence: 99%

See 1 more Smart Citation

Effects of exercise on brain functions in diabetic animal models

Yi¹

2015

WJD

View full text Add to dashboard Cite

Human life span has dramatically increased over several decades, and the quality of life has been considered to be equally important. However, diabetes mellitus (DM) characterized by problems related to insulin secretion and recognition has become a serious health problem in recent years that threatens human health by causing decline in brain functions and finally leading to neurodegenerative diseases. Exercise is recognized as an effective therapy for DM without medication administration. Exercise studies using experimental animals are a suitable option to overcome this drawback, and animal studies have improved continuously according to the needs of the experimenters. Since brain health is the most significant factor in human life, it is very important to assess brain functions according to the different exercise conditions using experimental animal models. Generally, there are two types of DM; insulin-dependent type 1 DM and an insulin-independent type 2 DM (T2DM); however, the author will mostly discuss brain functions in T2DM animal models in this review. Additionally, many physiopathologic alterations are caused in the brain by DM such as increased adiposity, inflammation, hormonal dysregulation, uncontrolled hyperphagia, insulin and leptin resistance, and dysregulation of neurotransmitters and declined neurogenesis in the hippocampus and we describe how exercise corrects these alterations in animal models. The results of changes in the brain environment differ according to voluntary, involuntary running exercises and resistance exercise, and gender in the animal studies. These factors have been mentioned in this review, and this review will be a good reference for studying how exercise can be used with therapy for treating DM.

show abstract

Section: Dm and Central Nervous Systemmentioning

confidence: 99%

Section: Effects Of Exercise On the Brain Of Diabetic Animalsmentioning

confidence: 99%

Effects of exercise on brain functions in diabetic animal models

Yi¹

2015

WJD

View full text Add to dashboard Cite

show abstract

“…Lira et al (2008) reportaram que 8 semanas de TF a 55-65 % do VO 2 máximo aumentaram a concentração de IL-10 no tecido adiposo mesentérico, elevando, desta forma, a razão IL-10/TNFα em ratos. Por outro lado, Gill et al (2003) O destreinamento físico promove rápido aumento da massa adiposa, ganho de massa corporal e resistência à insulina, tanto em humanos quanto em animais (PETIBOIS et al, 2004;YASARI et al, 2006;YASARI et al, 2007). Estudos em atletas de endurance altamente treinados mostraram que 7 a 10 dias de destreinamento físico reduziram significativamente a tolerância à glicose (ARCIERO, SMITH & CALLES-ESCANDON, 1998).…”

Section: Introductionunclassified

“…A sensibilidade à insulina em reposta a um teste oral de tolerância à glicose diminui rapidamente com a inatividade (ARCIERO, SMITH & CALLES- ESCANDON, 1998;, fato que pode estar associado à redução da quantidade de GLUT4 (HOST et al, 1998). Por outro lado, o destreino induz rápida diminuição da atividade da enzima lipase de lipoproteína presente no tecido muscular, aumento da lipemia pós-prandial, diminuição da concentração plasmática de HDL e aumento da concentração plasmática de LDL (YASARI et al, 2007).…”

Section: Introductionunclassified

“…Além disso, uma semana de destreinamento físico foi relacionada a aumento significativo na concentração plasmática de triacilgliceróis, tanto em jejum quanto no estado pós-prandial (GILL et al, 2003). (SHEPARD et al, 2001;PETIBOIS et al, 2004), sugerindo que esta condição representa um estado de pré-obesidade (YASARI et al, 2007). Foi demonstrado que a interrupção repentina do TF promove descontrole na ingestão alimentar, por mecanismos ainda pouco esclarecidos, podendo resultar em acúmulo de triacilgliceróis nos adipócitos (APPLEGATE, UPTON & STERN, 1984;LAMBERT et al, 1994;MUELLER, HERMAN & EIKELBOOM, 1999).…”

Section: Introductionunclassified

See 1 more Smart Citation

Suplementação crônica de leucina não impede a condição pró-inflamatória do destreinamento físico

Neto¹,

de²

View full text Add to dashboard Cite

Lifestyle and health‐related risk factors and risk of cognitive aging among older veterans

Yaffe

Hoang

Byers

et al. 2014

Alzheimer's & Dementia

View full text Add to dashboard Cite

Lifestyle and health-related factors are critical components of the risk for cognitive aging among veterans. Because dementia has a prolonged prodromal phase, understanding effects across the life course could help focus the timing and duration of prevention targets. This perspective may be especially relevant for veterans and health behaviors. Military service may promote development and maintenance of healthy lifestyle behaviors, but the period directly after active duty has ended could be an important transition stage and opportunity to address some important risk factors. Targeting multiple pathways in one intervention may maximize efficiency and benefits for veterans. A recent review of modifiable risk factors for Alzheimer's disease estimated that a 25% reduction of a combination of seven modifiable risk factors including diabetes, hypertension, obesity, depression, physical inactivity, smoking, and education/cognitive inactivity could prevent up to 3 million cases worldwide and 492,000 cases in the United States. Lifestyle interventions to address cardiovascular health in veterans may serve as useful models with both physical and cognitive activity components, dietary intervention, and vascular risk factor management. Although the evidence is accumulating for lifestyle and health-related risk factors as well as military risk factors, more studies are needed to characterize these factors in veterans and to examine the potential interactions between them.

show abstract

Effect of the detraining status on high-fat diet induced fat accumulation in the adipose tissue and liver in female rats

Cited by 20 publications

References 23 publications

Effects of exercise on brain functions in diabetic animal models

Effects of exercise on brain functions in diabetic animal models

Suplementação crônica de leucina não impede a condição pró-inflamatória do destreinamento físico

Lifestyle and health‐related risk factors and risk of cognitive aging among older veterans

Contact Info

Product

Resources

About