Effect of the FGF2 SNP11646 on milk production and fertility traits of Holstein cattle

Abstract

Th e objective of this study was to estimate the eff ect of a single-nucleotide polymorphism (SNP11646) in the FGF2 (Fibroblast Growth Factor 2) gene on the deregressed proof of breeding values (DRP) of Holstein sires (n = 149) for milk traits (milk yield, fat yield and percentage, and protein yield and percentage) and fertility (relative breeding value for own fertility -conception rate of heifers, cows, all females inseminated by the sperm of the sire; relative breeding value for conception rate of daughters -heifers, cows, all females). Th e diff erences between genotypes for milk performance were not signifi cant. Th e lowest DRP for milk performance were found for AA sires. For fertility, sires with this genotype had the best values both for the maternal genetic eff ect (conception rate of the daughters) and for the direct genetic eff ect (fertility of the sire). For conception rate of the daughters, in some cases, the diff erences reached the threshold of signifi cance. Th us, the results indicate coincidently with other studies the potential opposing eff ects on milk performance and fertility. FGF2 SNP11646 is still of interest for future cattle breeding studies.

Overview of SNPs Associated with Trans Fat Content in Cow’s Milk

“…Li et al [47] have shown that the SNP rs210169303 was linked to the highest 305-day milk yield. Brzáková et al [48] assessed the effect of SNP11646 in the FGF2 gene on the regressive evidence of the breeding value of sires in terms of reproductive qualities and milk production. The difference in milk production in animals with different genotypes was negligible.…”

Polymorphism of the fibroblast growth factor 2 gene (FGF 2) in Holstein cattle in the conditions of the Republic of Tatarstan

“…Частота аллелей A и G в чешской популяции голштинского скота составила 0,35 и 0,65, а частоты генотипов -0,13; 0,43 и 0,43 % для генотипов AA, AG и GG соответственно [3].…”