Effect of the main constituents of Pistacia lentiscus leaves against the DPPH radical and xanthine oxidase: experimental and theoretical study

Boucheffa, Saliha; Sobhi, Widad; Attoui, Ayoub; Selli, Serkan; Kelebek, Haşim; Semmeq, Abderrahmane; Benguerba, Yacine

doi:10.1080/07391102.2021.1936182

Cited by 7 publications

(6 citation statements)

References 85 publications

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“…The maximum values of polyphenols content are observed in the plants of the two sites S1.1 and S2.2, presenting the altitude of 1400 m and 720 m, respectively, with a significant difference ( p ≤ 0.05), compared to sites S1.2 and S2.1 (1120 m and 780 m, respectively) ( Figure 2 ). The results obtained in our study are in close agreement with those reported by Rodriguez-Perez et al [ 32 ], who identified different phenolic compounds in P. lentiscus L. leaves and are also confirmed by Boucheffa et al [ 33 ]. In comparison with other authors, Gardeli et al [ 34 ] found that the polyphenol content was 588 mg GAE/g in leaves of P. lentiscus.…”

Section: Resultssupporting

confidence: 93%

Valorization of Moroccan Pistacia lentiscus L. Leaves: Phytochemical and In Vitro Antioxidant Activity Evaluation Compared to Different Altitudes

Hadini

Azdimousa

Khoulati

et al. 2022

The Scientific World Journal

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This study examined the secondary metabolite content and the antioxidant activities of hydromethanolic P. lentiscus L. leaves extracts at different altitudes. The results indicated that the contents of polyphenols and flavonoids were significantly ( p ≤ 0.05 ) high in the low altitude, unlike the Chl (chlorophyll), tannins, and ascorbic acid, which were reported to have higher content in the high altitude. These results showed that the P. lentiscus L. is more adaptable to higher elevations than low elevation, where the plant was probably stressed. On the other hand, the analyses of correlation between the antioxidant activity and phytochemical content affirmed that the antiradical activity (DPPH) correlated with the content of polyphenols; however, the total antioxidant activity is correlated with the flavonoid content. These results revealed the importance of P. lentiscus L. leaves as a natural antioxidant and gave an idea of the altitude effect on the biochemical parameters of leaves.

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Section: Resultssupporting

confidence: 93%

Valorization of Moroccan Pistacia lentiscus L. Leaves: Phytochemical and In Vitro Antioxidant Activity Evaluation Compared to Different Altitudes

Hadini

Azdimousa

Khoulati

et al. 2022

The Scientific World Journal

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“…nipponica with methanol extraction. Similar results have been reported by Boucheffa et al [ 25 ] on Pistacia lentiscus leaves.…”

Section: Resultssupporting

confidence: 92%

Analyses of phytochemical compounds in the flowers and leaves of Spiraea japonica var. fortunei using UV-VIS, FTIR, and LC-MS techniques

Yılmazer Keskin,

Avcı,

Fajriana Febda Kurnia

2024

Heliyon

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“…Seven organic acid derivative compounds were identified by LC-QTOF-MS in the aqueous-alcoholic extract of P. (21,24,(26)(27)(28). Table 2 shows detailed information about the data of the molecules and fragments.…”

Section: Lc-qtof-ms Analysis Of Crude Extractmentioning

confidence: 99%

Investigation of Enzyme Inhibitory Activities, Antioxidant Activities, and Chemical Properties of Pistacia vera Leaves Using LC-QTOF-MS and RP-HPLC

2022

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: Since the leaves of some Pistacia species are used in traditional folk medicine for diabetes, this study investigated the in vitro antidiabetic effect (α-glucosidase and α-amylase) of Pistacia vera leaves. Additionally, the current study investigated the antihypercholesterolemic (cholesterol esterase), antiobesity (pancreatic lipase), and antioxidant activities (i.e., total antioxidant capacity, DPPH (2,2-Diphenyl-1-picrylhydrazyl) radical scavenging activity, metal chelating activity, and ferric-reducing antioxidant power) of P. vera leaves. The aqueous-alcoholic leaf extract inhibited α-amylase, α-glucosidase, and pancreatic lipase with the half-maximal inhibitory concentration values of 7.74 ± 0.72, 11.08 ± 3.96, and 168.43 ± 26.10 µg/mL, respectively. It was determined that the crude extract had high DPPH radical scavenging activity, ferric-reducing power, and moderate metal chelating activity. The ethyl acetate (EtOAc) subextract obtained by the liquid-liquid fractionation of the crude extract showed potent α-amylase and α-glucosidase inhibitory activities. The EtOAc subextract (5.794 ± 0.027 g/100 g subextract) was standardized by reversed-phase high-performance liquid chromatography based on β-pentagalloyl glucose, which showed inhibitory effects on both amylase and glucosidase enzymes. Fifteen compounds, seven of which are organic acid derivatives and eight of which are flavonoids, were identified by liquid chromatography quadrupole time-of-flight mass spectrometry (LC-QTOF-MS) analysis in the crude extract of P. vera leaves. Seven of the fifteen phenolic compounds detected in the crude extract by LC-QTOF-MS have both glucosidase and amylase inhibitory effects. As a result, P. vera leaves can be a potential source for compounds with high antioxidant effects that show inhibitory effects on enzymes involved in carbohydrate digestion in the prevention and treatment of diabetes or can be evaluated as a standardized extract.

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Effect of the main constituents of Pistacia lentiscus leaves against the DPPH radical and xanthine oxidase: experimental and theoretical study

Cited by 7 publications

References 85 publications

Valorization of Moroccan Pistacia lentiscus L. Leaves: Phytochemical and In Vitro Antioxidant Activity Evaluation Compared to Different Altitudes

Valorization of Moroccan Pistacia lentiscus L. Leaves: Phytochemical and In Vitro Antioxidant Activity Evaluation Compared to Different Altitudes

Analyses of phytochemical compounds in the flowers and leaves of Spiraea japonica var. fortunei using UV-VIS, FTIR, and LC-MS techniques

Investigation of Enzyme Inhibitory Activities, Antioxidant Activities, and Chemical Properties of Pistacia vera Leaves Using LC-QTOF-MS and RP-HPLC

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