Effect of the Mg:Al Ratio on Borate (or Silicate)/Nitrate Exchange in Hydrotalcite

Mg,Al layered double hydroxides with intercalated indomethacin: Synthesis, characterization, and pharmacological study

“…The maxima corresponding to diffraction by the basal planes are recorded at 23.5, 11.7, and 7.8 Å, corresponding to planes (003), (006), and (009), respectively. The reversed intensities of lines due to planes (006) and (009) has been observed previously for other LDH compounds and is due to different planar electron densities 33,34. From the basal spacing, and considering the width of the brucite layer (4.8 Å35), the height of the gallery results 18.7 Å, slightly lower than the value reported by Ambrogi et al,30 (19.9 Å) for samples prepared by anion exchange from a Mg,Al–Cl precursor, showing that the synthetic route can affect the precise orientation of the molecules in the interlayer.…”

On the Adsorption of Tetracycline by Calcined Magnesium‐Aluminum Hydrotalcites

“…Th e lattice parameter a, characteristic of the average metalmetal distance within the brucite-like layers, could be calculated using the (110) refl ection and was found to be 0.304, 0.306, and 0.307 nm for HT-2.0, HT-2.9, and HT-4.4, respectively. Th ese values refl ect the increasing distance between neighboring octahedra in the brucite-like layers with decreasing Al content in the layers due to the smaller radii of Al 3+ (0.067 nm) compared to Mg 2+ (0.086 nm) in octahedral coordination (Del Arco et al, 2000). (Takehira et al, 2005).…”

The in vitro and in vivo anti-tumor effect of layered double hydroxides nanoparticles as delivery for podophyllotoxin

“…In recent years, LDH has been found to possess promising applications in biomedicine due to their unique anion exchange capability, controlled release and protection of the payload. Many LDH compounds intercalated with bioorganic anions such as DNA (Choy et al, 1999(Choy et al, , 2001Kwak et al, 2004;Hofer et al, 2004), amino acids (Aisawa et al, 2001;Zhang et al, 2004;Hibino and Nishiyama, 2004;Wong et al, 1999;Nakayama et al, 2002), anionic polymers (Wang et al, 2005), pesticides (Zhang et al, 2005(Zhang et al, , 2006, and drugs (Ambrogi et al, 1995;Li et al, 2004;Del Arco et al, 2000;Gutierrez et al, 1995;Qin et al, 2008) have been prepared successfully. Special interests have focused on exploring the possibilities of using LDH-drug delivery systems to deliver anti-inflammatory (Ambrogi et al, 2006) or anti-cancer drugs (Tyner et al, 2004).…”