Effect of the β-Adrenergic Agonist Cimaterol (CL 263,780) on the Growth and Carcass Characteristics of Finishing Swine

Abstract

A randomized complete-block design was used to evaluate the effects of the beta-adrenergic agonist, cimaterol (CL 263,780), on growth rate, feed efficiency and carcass composition of finishing swine. The drug was fed at four levels (0, .25, .5 and 1.0 ppm) to a total of 240 pigs from 64.5 to 103.7 kg live weight. Growth rate and feed efficiency were measured during the 7-wk feeding trial. Feeding cimaterol depressed feed intake, improved feed efficiency and did not alter rate of gain. Carcass evaluation showed that pigs continuously fed cimaterol had 13.2, 9.3 and 9.2% less fat measured at the 10th rib, P2 and average backfat (BF) locations, respectively, compared with controls. Cimaterol-fed pigs had increased loin eye areas (10.9%), and increased semitendinosus (11.8%) and biceps femoris (8.9%) weights compared with controls. The semitendinosus muscles of the cimaterol-fed pigs had less fat and the femur bones were shorter and lighter weight than controls. There were no detected differences in structural soundness of the live pigs, but postmortem evaluation of the hooves indicated that pigs fed 1.0 ppm cimaterol had a higher incidence of hoof lesions. Pigs withdrawn from cimaterol for 7 d were comparable in performance and carcass characteristics with those continuously fed the drug except that carcass fat measurements had generally returned to control values. The data indicate that cimaterol improved the feed efficiency of finishing pigs and increased the lean:fat ratio of their carcasses. Withdrawal of cimaterol caused compensatory fat deposition.

Qualidade da carne de fêmeas suínas alimentadas com diferentes concentrações de ractopamina na dieta

“…Jones et al (1985) relataram que o uso de agonistas β adrenérgicos nas dietas leva à produção de uma carne suína mais dura. Warris et al (1991), ao compararem os resultados da análise sensorial com a avaliação mecânica da força de cisalhamento, em carne de suínos alimentados com dietas contendo agonistas β adrenérgicos, observaram aumento da força de cisalhamento, porém não detectado pela análise sensorial.…”

The effect of the β-2-adrenergic agonist clenbuterol or implantation with oestradiol plus trenbolone acetate on protein metabolism in wether lambs

“…chickens (Dalrymple et al 1983;, pigs (Jones et al 1985), lambs Dalrymple et al 1985;Beermann et al 1985b) and steers (Ricks et al 1984). The effects on the carcass lipid content are dramatic and are readily discernible even by a casual visual inspection of the carcass.…”

Effect or ractopamine on growth and body composition of pigs during compensatory growth

“…Crome et al (1996) reported that ham bone weight as a percentage of the trimmed ham decreased due to ractopamine. Likewise, pigs fed the bAR agonist cimaterol had shorter and lighter femurs compared with control pigs (Jones et al, 1985).…”