Effect of three-year consumption of erythritol, xylitol and sorbitol candies on various plaque and salivary caries-related variables

Runnel, Riina; Mäkinen, Kauko K.; Honkala, Sisko; Olak, Jana; Mäkinen, Pirkko‐Liisa; Nõmmela, Rita; Vahlberg, Tero; Honkala, Eino; Saag, Mare

doi:10.1016/j.jdent.2013.09.007

Cited by 57 publications

(66 citation statements)

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“…Calibrations were arranged during 2 days before every annual examination. Consistency of the ICDAS codes by each of the examiners and between the examiners was very high (κ > 0.9) [Runnel et al, 2013b].…”

Section: Methodsmentioning

confidence: 93%

Effect of Erythritol and Xylitol on Dental Caries Prevention in Children

et al. 2014

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Objective: The aim of this study was to test the efficacy of long-term, daily intake of erythritol and xylitol candy, compared with sorbitol candy, on the development of enamel and dentin caries lesions. Methods: The study was a double-blind randomized controlled prospective clinical trial. Altogether 485 primary school children, first- and second-graders at baseline, from southeastern Estonia participated in this 3-year intervention. Each child consumed four erythritol, xylitol or sorbitol (control) candies three times per school day. The daily intake of polyol was about 7.5 g. The International Caries Detection and Assessment System (ICDAS) was used in the clinical examinations by four calibrated examiners at baseline and at 12, 24 and 36 months. Results: The annual examination analyses and the follow-up analyses confirmed that the number of dentin caries teeth and surfaces at 24 months follow-up and surfaces at 36 months follow-up was significantly lower in the mixed dentition in the erythritol group than in the xylitol or control group. Time of enamel/dentin caries lesions to develop and of dentin caries lesions to progress was significantly longer in the erythritol group compared to the sorbitol and xylitol groups. Also the increase in caries score was lower in the erythritol group than in the other groups. Conclusions: In the follow-up examinations, a lower number of dentin caries teeth and surfaces was found in the erythritol group than in the xylitol or control groups. Time to the development of caries lesions was longest in the erythritol group. Trial registration: ClinicalTrials.gov Identifier NCT01062633.

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Section: Methodsmentioning

confidence: 93%

Effect of Erythritol and Xylitol on Dental Caries Prevention in Children

et al. 2014

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“…Using chewing gum (1.33 g of xylitol in 1 piece 4 times per day) over 3 months is sufficient to prevent the increase of SM count in plaque [33]. Research by Runnel et al [34] suggests that the efficacy of xylitol in caries prophylaxis may depend not only on the frequency of administration during the day but also on an even disposition of servings in time; also, a discontinuation of application, despite its latter resumption, might be significant. In conditions when retaining the usual routine of hygiene is impossible, chewing gum containing xylitol not only reduces the increment of bacteria in saliva but also improves the subjective evaluation of personal oral cavity condition [35].…”

Section: Discussionmentioning

confidence: 99%

Xylitol Content in Dental Care and Food Products Available on the Polish Market and Their Significance in Caries Prevention

Turska‐Szybka¹,

Pasternok²,

Olczak‐Kowalczyk³

2016

Dent. Med. Probl.

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Sugar alcohols (or polyols), natural organic compounds, may be used in order to replace sucrose. There are many sugar alcohols administered in dental care and food products, such as maltitol, lactitol, sorbitol, mannitol, erythritol and xylitol.Xylitol (E 967) is a five-carbon sugar alcohol of crystalline structure and sweetness similar to sucrose and has the same relative sweetness, which is 1, and provides less energy compared to sucrose (2.4 kcal vs 4 kcal). It occurs naturally in certain fruits, such as plums, raspberries and strawberries, and in birch trees; it is also developed in the digestive reactions of the human body in the amount of 15 g/day. It can be industrially produced using products rich in xylans, such as corncobs and birch wood. Xylitol obtained in the reduction reaction of xylose in the presence of catalytic converters is used in the food and cosmetic industry as an ingredient of chewing gum, lozenges, sprays, mouth rinses, gels, toothpastes, wipes, candies and AbstractCaries pertains to most of the Polish community and is associated with a high intake of sucrose and monosaccharides. Their non-cariogenic analogue is xylitol -equally sweet as sucrose, but not metabolized by the majority of bacteria existing in the oral cavity. The aim of this paper is to evaluate the content of xylitol in dental care and food products available on the Polish market and their significance in caries prevention. The products were selected based on the literature, informational leaflets and information from manufacturers. The toothpastes and gels taken into consideration contain up to 25% xylitol, mouth rinses -25%, dental care sprays -35%, chewing gum -66-67% and candies -96%. A large number of dental care and food products recommended in caries prevention contain xylitol in diverse concentrations. If caries-producing sugars are replaced with non-cariogenic sugar alcohols, the frequency of caries may be diminished. On one hand, xylitol, as an acknowledged anti-carious agent, is included in many caries-prevention programs, in precise concentrations and regularly used, on the other hand -there is a lack of EBM (Evidence-Based Medicine) data indicating the effectiveness of xylitol, apart from those pertaining to fluoride toothpastes with the addition of xylitol. It is emphasized that more detailed trials are necessary to answer the question whether it is xylitol that is relevant in caries prevention or the alteration of habits -lessened sucrose intake or its complete substitution with a sweetener and the act of chewing, which stimulates salivation (Dent. Med. Probl. 2016, 53, 4, 542-550).

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“…Аналіз літературних джерел дозволив встановити, що всі наявні методи профілактики карієсу мають етіотропну спрямованість, що включає боротьбу з карієсогенною мікрофлорою ротової порожнини та усунення продуктів її життєдіяльності, або патоге-нетичну, яка полягає в підвищенні резистентності твердих тканин зубів [2,5,7,27,29]. Більшість сучасних карієспрофілактичних заходів ґрунтують-ся на використанні сполук фтору, вітамінно-мінеральних комплексів, імунокоригуючих препара-тів на державному, регіональному чи індивідуаль-ному рівнях [5,7,8,11,31].…”

Section: огляд літературиunclassified

“…Medical Minerals", за свід-ченням авторів забезпечувало зниження обсіменін-ня поверхні зубної бляшки Streptococcus mutants із 73,3% до 40%, а також відновленні популяції вейл-лонел -як головного антагоніста карієсогенної мікрофлори [12]. Установлено, що вживання жува-льної гумки з ксилітом сприяє зниженню ризику переносу карієсогенних мікроорганізмів від матері до дитини та зниженню ризику виникнення карієсу в дітей раннього віку [29].…”

Section: огляд літературиunclassified

Prevention of Dental Caries in Children as a Fundamental Success of General Dental Health of the Population

Oktysiuk¹

2018

Ukr. ž. med. bìol. sportu

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Effect of three-year consumption of erythritol, xylitol and sorbitol candies on various plaque and salivary caries-related variables

Cited by 57 publications

References 12 publications

Effect of Erythritol and Xylitol on Dental Caries Prevention in Children

Effect of Erythritol and Xylitol on Dental Caries Prevention in Children

Xylitol Content in Dental Care and Food Products Available on the Polish Market and Their Significance in Caries Prevention

Prevention of Dental Caries in Children as a Fundamental Success of General Dental Health of the Population

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