Previous studies in the long-term experiments at Pendleton, OR (USA), were focused on organic matter cycling, but the consequences of land management for nutrient status over time have received little attention. Soil and wheat (Triticum aestivum L.) tissue samples were analyzed to determine the macronutrient dynamics associated with residue management methods and fertilizer rate under a dryland winter wheat-fallow rotation. The treatments included: no burn residue incorporation with farmyard manure (FYM) or pea vines, no burn or spring burn with application of N fertilizer (0, 45, and 90 kg ha −1), and fall burn wheat residue incorporation. The results revealed no differences on the effect of residue burning on macronutrient concentration over time. After receiving the same treatments for 84 years, the concentrations of soil organic C, total N and S, and extractable Mg, K, P in the 0-10 cm depth significantly increased in FYM plots compared to the rest of the plots. The N fertilization rate of 90 kg ha −1 reduced the accumulations of P, K, and Ca in grain compared to the 0 and 45 kg N ha −1 applications. The results indicate that residue incorporation with FYM can play vital role in reducing the macronutrient decline over time. Crop yields are no longer increasing at the rate of a couple of decades ago 1 and, simultaneously, the proportion of arable lands are also constantly shrinking 2-a condition that demands increased cultivation under dryland cropping systems. Therefore, examining various soil management practices and their impacts on soil quality, such as macronutrient status, of such regions may contribute to sustainable food production for the next 100 years. Despite the important roles of macronutrients for plant growth, few studies have evaluated their dynamics under dryland cropping systems over extended periods of time. The drylands of the Pacific Northwest (PNW) receive an average annual precipitation of 150-437 mm 3 , while winter wheat requires 500-580 mm of water to complete its lifecycle 4 , and hence, annual dryland wheat production may not be successful in this region. To overcome this water limitation, farmers in this production region of more than two million hectares have opted to utilize a winter wheat-14 months fallow (WW-F) rotation for over 100 years. This system has so far been proven to be economical and stable 5. In the WW-F cropping system, wheat is grown for ten months and the land is in fallow for 14 months to conserve winter precipitation for next year's wheat 6,7. However, during these 14 months of fallow, the surface is exposed to general degradation, wind erosion, and accelerated C and N losses 6. Nevertheless, the WW-F cropping system has proven to be the best solution to sustain wheat production in these regions 7 , therefore, management strategies that can maintain or enhance long-term soil productivity are crucial for this region. Wheat residue burning was a common soil management method during the 1930's in the WW-F cropping system 6 , and is still being practiced by some f...