Effect of Tween 20 on the Properties of Stearate Oleogels: an in‐Depth Analysis

Abstract

stress (either thermal or mechanical) was introduced, the strength of the oleogels was decreased due to the syneresis of oil through the pores. An increase in the Tween 20 concentration-dependent relaxation of the oleogels was also observed due to the polymorphic change and arrangement of the gelators.

Stearic Acid Modified Stearyl Alcohol Oleogel: Analysis of the Thermal, Mechanical and Drug Release Properties

“…Visual observation of the oleogels suggested that the addition of stearic acid results in oleogels with a homogenous matrix, which can be explained by the formation of mixed crystals when fatty acid-fatty alcohol mixtures are used for structuring of the oils [30]. A slight alteration in the crystal habit completely changes the architecture of the gelator network and hence their texture [13,14]. Microscopic results indicated that stearic acid promoted the formation of long gelator fibers.…”

“…An alteration in the microstructure alters the spaces available in between the gelator network structure. The formation of plate-like structure hinders solute migration [14]. On the contrary, the formation of fiber-like structures promotes solute migration [32].…”

“…Gelation kinetics of the oleogels was analyzed using an in-house developed instrument. The details of the in-house developed machine have been reported earlier by our group [13,14].…”

“…Based on the thermal profiles of oleogels, it is possible to determine the change in the solid fat content (SFC) of the oleogels [13,14]. The %SFC was calculated from the DSC thermograms using Proteus software (Netzsch, Germany), provided by the manufacturer.…”

“…2; Fig. 3b) to determine the rate of melting (K H ) of the gelator molecules with temperature [13,14]. The negative values of 'K H ' are due to the inverse logistic SFC profile, obtained during the heating process.…”