Effect of Vehicles on Topical Application of Aloe Vera and Arnica Montana Components

Bergamante, Valentina; Ceschel, G. C.; Marazzita, Sergio; Ronchi, Celestino; Fini, Adamo

doi:10.1080/10717540701202960

Cited by 16 publications

(12 citation statements)

References 20 publications

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“…1). This result could be responsible for the popular use of A. barbadensis gel and leaf to relieve different types of gastrointestinal irritations, skin irritations, upper respiratory tract, intestinal tract, and urinogenital infections [5,7]. The gel is also known to promote wound healing due to the presence of active components like anthraquinones and chromones [16].…”

Section: Resultsmentioning

confidence: 99%

“…Aloe gel has been used for a long time for topical treatment of skin irritations, but aloe can also be used as a beverage and aloe products are considered to provide relief from constipation. Aloe extract can be taken orally as a dietary supplement, even though it does not have FDA approval to be used as a drug [5]. A. vera gel is the leaf pulp of mucilage, a thin clear jelly-like substance obtained from the parenchymal tissue that makes the inner portion of the leaves [6].…”

Section: Introductionmentioning

confidence: 99%

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Antibacterial Activities of Crude Extract of Aloe barbadensis to Clinically Isolated Bacterial Pathogens

Pandey

Mishra

2009

Appl Biochem Biotechnol

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The antibacterial activity of Aloe barbadensis was tested on clinically isolated bacterial pathogens i.e. Enterococcus bovis, Staphylococcus aureus, Escherichia coli, Proteus vulgaris, Proteus mirabilis, Pseudomonas aeruginosa, Morganella morganii, and Klebsiella pneumoniae causing infection in human being. Ethanolic and aqueous extracts were used for the antibacterial effect, which was measured by the appearance of zone of inhibition. Relatively higher MIC concentrations were obtained for gram negative bacteria E. coli and K. pneumoniae, with ethanol extract; however, no inhibitory effect was noted for aqueous extract. Ethanolic extract possesses great inhibitory activity for gram positive bacteria, E. bovis followed by S. aureus. Among gram negative bacteria, highest inhibitory effect was observed with P. aeruginosa, followed by M. morganii, P. mirabilis, and P. vulgaris, which was significant (p < 0.01) than E. coli and K. pneumoniae. Antimicrobial activity tests of crude extract of A. barbadensis were carried out to validate the use of traditional medicinal herbal and results of this study tend to give credence to the common use of A. barbadensis gel and leaf.

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Section: Resultsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Antibacterial Activities of Crude Extract of Aloe barbadensis to Clinically Isolated Bacterial Pathogens

Pandey

Mishra

2009

Appl Biochem Biotechnol

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“…However, extracts of aloe vera have been shown to have beneficial heterogenous properties including the ability to penetrate and anaesthetize tissue, preclude bacterial, fungal and viral growth, act as an anti-inflammatory agent, facilitate wound healing and to affect cell proliferation, cellular interactions and other physiological processes [49][50][51][52][53][54]. On the other hand, it has been demonstrated that some components of aloe vera may increase the sensitivity of skin to ultraviolet light [55,56]. Although it has been demonstrated that aloe vera contains some antioxidant capacity [57,58], we were not able to detect any antioxidant capacity in the aloe vera extract.…”

Section: Discussionmentioning

confidence: 99%

Antioxidant capacity of 3D human skin EpiDerm^TM model: effects of skin moisturizers

Grazul-Bilska

Bilski

Redmer

et al. 2009

Intern J of Cosmetic Sci

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The objective of this study was to determine the effects of skin moisturizers on total antioxidant capacity (TAC) of human skin using EpiDerm model. Three different skin moisturizers containing antioxidant ingredients (samples 1-3) or aloe vera extract were topically applied to EpiDerm units and incubated for 2 and 24 h to determine acute and longer-term effects of applied samples on TAC and glutathione peroxidase activity in medium and/or homogenized skin tissues. Total antioxidant capacity in medium and skin homogenates was enhanced (P < 0.0001) by gel containing antioxidant ingredients (sample 2) after 2 and 24 h of incubation. Total antioxidant capacity in medium was also enhanced (P < 0.001) by cream containing antioxidant ingredients (sample 3) after 24 h of incubation. Overall, TAC in medium was greater (P < 0.02) after 24 h than 2 h of incubation. Skin moisturizer cream with high antioxidant levels determined by using oxygen radical absorbance capacity testing (sample 1) and aloe vera extract did not affect TAC. Glutathione peroxidase activity was enhanced (P < 0.0001) in medium and skin homogenates by sample 2 but not by any other sample. These data demonstrate high potential of gel and cream (samples 2 and 3) containing antioxidant ingredients in enhancing antioxidant capacity of EpiDerm which will likely contribute to overall skin health. Results of this experiment will help to better understand mechanisms of effects of skin moisturizers containing antioxidant ingredients on skin function at the tissue level and to establish effective strategies for skin protection and clinical treatments of skin disorders and possibly healing wounds.

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“…Bergamante et al 28 investigated the ability to dissolve, release, and induce the permeation of helenalin (flavonoid responsible for the anti-inflammatory activity of the Arnica montana extract) in two types of gels and microemulsions. Their study showed that a microemulsion could be a good vehicle to increase the permeation of helenalin.…”

Section: Ganzera Et Almentioning

confidence: 99%

Arnica montana does not affect mast cell populations in experimentally induced oral ulcers in rats

Perussolo¹,

Grégio²,

Azevedo‐Alanis³

et al. 2015

Medical Express

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BACKGROUND:Studies have shown that Arnica montana shows anti-inflammatory and antioxidant activities. It has been used in traditional medicine for the treatment of several disorders. The aim of this study was to investigate the effect of Arnica montana on mast cells during the wound healing of oral ulcers. METHOD: An ulcerated lesion was chemically induced on the tongue of 75 male albino rats and, then, treated topically for seven days using saline solution (control), Arnica montana gel or tincture. The animals were killed after 2

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Effect of Vehicles on Topical Application of Aloe Vera and Arnica Montana Components

Cited by 16 publications

References 20 publications

Antibacterial Activities of Crude Extract of Aloe barbadensis to Clinically Isolated Bacterial Pathogens

Antibacterial Activities of Crude Extract of Aloe barbadensis to Clinically Isolated Bacterial Pathogens

Antioxidant capacity of 3D human skin EpiDerm^TM model: effects of skin moisturizers

Arnica montana does not affect mast cell populations in experimentally induced oral ulcers in rats

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Effect of Vehicles on Topical Application of Aloe Vera and Arnica Montana Components

Cited by 16 publications

References 20 publications

Antibacterial Activities of Crude Extract of Aloe barbadensis to Clinically Isolated Bacterial Pathogens

Antibacterial Activities of Crude Extract of Aloe barbadensis to Clinically Isolated Bacterial Pathogens

Antioxidant capacity of 3D human skin EpiDermTM model: effects of skin moisturizers

Arnica montana does not affect mast cell populations in experimentally induced oral ulcers in rats

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Product

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Antioxidant capacity of 3D human skin EpiDerm^TM model: effects of skin moisturizers