Effect of viable or dead<i>Lactobacillus casei</i>organisms administered orally to mice on resistance against<i>Trichinella spiralis</i>infection

Garfias, Carlos Ramón Bautista; Ixta-Rodríguez, Olga; Martinez-Gomez, F.; López, Mercedes G.; Aguilar-Figueroa, Blanca Rosa

doi:10.1051/parasite/200108s2226

Cited by 66 publications

(45 citation statements)

References 5 publications

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“…This result is in agreement with Bautista-Garfias et al (2001) who revealed that the stimulation of immune response by Lactobacillus spp. that caused decease in worm counts at the stage of oviposition.…”

Section: Discussionsupporting

confidence: 83%

“…This result is in agreement with Abdel-Salam et al (2008) who reported that probiotic labneh containing garlic and onion oil have a protective effect against worm burden of S. mansoni infected mice compared with control infected. Also, Bautista-Garfias et al (2001) reported that significant reduction in the number of adult Trichinella spiralis worms in the intestine and of larvae per gram of muscle tissue was observed in the mice treated with L. casei before infection …”

Section: Discussionmentioning

confidence: 99%

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Effect of Lactobacillus sporogenes (probiotic) on certain parasitological and molecular aspects in Schistosoma mansoni infected mice

et al. 2014

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The prospective effects of Lactobacillus sporogenes (probiotics) and/or praziquantel (PZQ) treatment on some parasitological, histological and molecular aspects in Schistosoma mansoni infected mice were studied. The present data recorded that combination between PZQ (300 mg/Kg one dose 7 weeks post infection) and L. sporogenes (12.5 million spore/mice/week for 8 weeks from the first day of infection) reduced worm and ova count. Also, oogram patterns in liver and intestine recorded that treatment with L. sporogenes alone increase number of dead eggs especially in intestine. Histological observations showed significant (P \ 0.05) reduction in the mean values of granuloma diameters in liver and intestine in infected mice groups treated with PZQ and/or L. sporogenes. Single strand breaks (comet assay) showed increase in number of damaged and strong damaged lymphocyte cells in mice infected with S. mansoni and infected treated with PZQ while L. sporogenes administration reduced DNA damage. Flow cytometry also confirmed role of L. sporogenes in reducing significantly DNA damage according to determination of cell cycle analysis apoptosis. It can be concluded that administration of L. sporogenes accompanied with PZQ treatment ameliorates the hepatic and intestinal damage caused by S. mansoni infection.

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Section: Discussionsupporting

confidence: 83%

Section: Discussionmentioning

confidence: 99%

Effect of Lactobacillus sporogenes (probiotic) on certain parasitological and molecular aspects in Schistosoma mansoni infected mice

et al. 2014

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“…Além da redução do número de vermes, os animais tratados apresentaram maior infiltração de células mononucleares, menor número de mastócitos na mucosa e não apresentaram encurtamento das vilosidades intestinais. Em um segundo experimento, lactobacilos vivos ou mortos ou sobrenadante de cultura foram administrados por via oral a camundongos experimentalmente infectados (BAUTISTA-GARFIAS et al, 2001). A redução da carga parasitária foi mais expressiva nos animais que receberam lactobacilos vivos, porém, nos que receberam lactobacilos mortos ou sobrenadante de cultura, o número de vermes recuperados foi inferior ao dos animais controles.…”

Section: Os Efeitos De Probióticos Nas Infecções Porunclassified

Potencial bioterapêutico dos probióticos nas parasitoses intestinais

Oliveira-Sequeira¹,

Ribeiro²,

Gomes³

2008

Cienc. Rural

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“…Whereas probiotics have been used successfully for the treatment of several intestinal disorders (Heyman 2000, de Vrese & Schrezenmeir 2008, they have not yet been applied for the control of human intestinal parasitoses. However, they have been used successfully in animals for the treatment of parasitoses, such as cryptosporidiosis, giardiasis, trichinellosis and babesiosis (Alak et al 1999, Bautista-Garfias et al 2001, Humen et al 2005. In contrast, Dea-Ayuela et al (2008) (Sparo et al 2006).…”

mentioning

confidence: 99%

In vitro and in vivo effects of Enterococcus faecalis CECT7121 on Toxocara canis

Chiodo

Sparo

Pezzani

et al. 2010

Mem. Inst. Oswaldo Cruz

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The aim of the present paper was to evaluate the larvicidal effect of Enterococcus faecalis CECT7121 (Ef7121) on the Toxocara canis cycle both in vitro and in vivo. For the in vitro experiments, T. canis larvae were incubated with the supernatants of Ef7121 (EI) and mutant Ef7121 (EIm), in a pre-culture of Ef7121 (EII) and in a fresh culture with Ef7121 (EIII) and the Ef7121 mutant strain (EIIIm). The viability of the larvae was calculated after a 48 h incubation. A significant reduction of the viability of T. canis larvae was observed in EI, EII and EIII. A decrease of this inhibitory effect was observed in EIm and EIIIm (p = 0.008). In the in vivo experiments, mice were orally inoculated with three doses of Ef7121. To study the probiotic persistence in the intestine, the animals were sacrificed every four days and their intestines were dissected. The initial average bacterial levels were 9.7 x 10(4) for Ef7121 (colony forming units/g). At the end of the assay the levels were 1.46 x 10(4). No bacterial translocation was detected in mesenteric lymphatic nodules and spleen. Ef7121 interference with the biological cycle was evaluated in mice challenged with T. canis. The interference was significant when the mice were challenged with probiotic and T. canis simultaneously (p = 0.001), but it was not significant when the challenge was performed 15 days after administration of the bacterial inoculum (p = 0.06). In conclusion, Ef7121 possessed in vitro and in vivo larvicidal activity

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Effect of viable or deadLactobacillus caseiorganisms administered orally to mice on resistance againstTrichinella spiralisinfection

Cited by 66 publications

References 5 publications

Effect of Lactobacillus sporogenes (probiotic) on certain parasitological and molecular aspects in Schistosoma mansoni infected mice

Effect of Lactobacillus sporogenes (probiotic) on certain parasitological and molecular aspects in Schistosoma mansoni infected mice

Potencial bioterapêutico dos probióticos nas parasitoses intestinais

In vitro and in vivo effects of Enterococcus faecalis CECT7121 on Toxocara canis

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