EFFECT OF VIRGIN OLIVE OIL (&lt;i&gt;OLEA EUROPEA&lt;/i&gt;. L) ON KIDNEY FUNCTION IMPAIRMENT AND OXIDATIVE STRESS INDUCED BY MERCURIC CHLORIDE IN RATS

Necib,

doi:10.3844/ajbbsp.2013.415.422

Cited by 14 publications

(15 citation statements)

References 45 publications

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“…In the present study, decrease serum ALT and AST agrees with Okukpe et al (2011) who reported that omega3 fatty acids in food reduced the AST& ALT level. Our results are also similar with Necib et al (2013) who reported significant (P<0.01) decreased in the serum ALT activities after treating the rats with olive oil 2 ml. The variable effects of olive oil supplementation on biochemical constituents of Teddy buck and other animals or bird might be due to variation in enzymatic differences in the digestive process Our results shown that serum triglyceride significantly decrease (P<0.05) as compared to untreated group which are in line with Wani et al (2015) who reported the consequence of olive oil in contradiction of high fat diet in mice.…”

Section: Table 1 Serum Biochemical Metabolites and Hormonal Profile supporting

confidence: 92%

Effects of feed supplementation with olive oil on serum testosterone, triiodothyronine, thyroxine and some biochemical metabolites in Teddy goat bucks

Farooq¹,

Ali²,

Jamil³

et al. 2017

EJEA

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Teddy is highly proliferative goat breed, as female of this breed are famous for high twining rates. Feed supplementation of olive oil has been shown to improve semen quality of goat bucks. In this study, the effect of feed supplementation with olive oil on serum testosterone, triiodothyronine (T3), thyroxine (T4) and some biochemical metabolites in teddy goat bucks were investigated. For this purpose, 9 adult male goats, with clinically normal reproductive tract, were randomly separated into by three equal assemblies A, B and C. Animals in Cluster A were fed control ration (control group), whereas goats in group B and C were nourished with complemented 15 and 30 ml Olive oil, respectively, in morning daily for 8 weeks. Blood was collected weekly from each experimental animal and analyzed for serum testosterone, T3 and T4 concentration through ELISA. Similarly, serum alanine aminotransferase (ALT), Aspartate aminotransferase (AST), total cholesterol, triglycerides and glucose were determined using commercially available kits. Results revealed that serum concentrations of testosterone, T3 and T4 were higher (P<0.05) in bucks of groups B and C compared to those of control group. However, differences in concentration of these hormones between bucks of the former two groups were non-significant. Among biochemical metabolites, serum ALT, total cholesterol and triglycerides differed significantly (P<0.05) among three groups, with highest in control group and lowest in group C. Serum AST activity was also lower in bucks of assembly B and C than control, but, changes between groups B and C were non-significant. Similarly, the treatment had no effect on serum glucose concentrations. Based on results of the present studies, it was concluded that feed supplementation of olive oil improves semen quality and libido of Teddy goat bucks. However, its effects on health biomarkers and fertility rates of buck may be investigated before making any recommendation.

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Section: Table 1 Serum Biochemical Metabolites and Hormonal Profile supporting

confidence: 92%

Effects of feed supplementation with olive oil on serum testosterone, triiodothyronine, thyroxine and some biochemical metabolites in Teddy goat bucks

Farooq¹,

Ali²,

Jamil³

et al. 2017

EJEA

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“…Again, serum urea level was compared between depressed control and depressed mushroom supplemented group and the difference was highly significant. Similar findings were also reported by different researchers but they use virgin olive oil supplementation 9 .…”

Section: Discussionsupporting

confidence: 79%

“…Some other investigators observed that serum urea, creatinine and uric acid levels were significantly increased after 2 weeks treatment with oxidative stress induced by mercuric chloride(0.5 mg/ kg bw) 9 .In a longitudinal study (5days to 11 years)it has been shown that the individuals with depressive symptoms may develop rapid declines in kidney function and hospitalization occur with acute kidney injuryduring follow-up 10 .…”

Section: Introductionmentioning

confidence: 99%

Effect of Oyster Mushroom on Kidney in Stress Induced Depressed Rats

Jahan¹,

Akhter

Sultana

2017

J Bangladesh Soc Physiol

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Background: Depression is associated with stressful condition which may cause kidney damage. Oyster mushroom (plurotus florida) may have free radical scavenging activity thereby can be used for the prevention and treatment for kidney damage. Objective: to observe the effect of oyster mushroom (plurotus florida) on kidney in restraint stress induced depressed rats. Methods: This experimental study was conducted from July 2012 to June 2013 in the Department of Physiology, Sir Salimullah Medical College( SSMC), Mitford, Dhaka. Thirty Wister albino male rats, aged 90 to 100 days, weighing 150 to 180g (initial body weight) were used in the present study. Then they were divided into Group I (Control group, without mushroom n=20) and Group II (Experimental group, depressed rats supplemented with mushroom n=10). Control group without mushroom again subdivided into Group Ia,( baseline control n=10) and Group Ib (depressed control n=10) . All groups of animals were received basal diet for 28 consecutive days started from the 1 st day of the study period. Group Ib (depressed control) and group II (depressed mushroom supplemented) were housed under controlled condition in rat immobilizer (made up of steel wire, measuring 9´´ x 2.75´´ of light weight) for 6 hour/day for 28 days for the development of stress induced depression. In addition, only group II received oyster mushroom extract (200 mg/kg body weight, orally) for the same period. One rat of Group Ib (depressed control) was expired after 10 days for unknown cause. All 29 rats were sacrificed on day 30. Then blood sample and kidneys specimen were collected. Initial (initial bw ) and final body weights (final bw) were measured. Then estimation of blood glucose and serum urea levels were done by standard laboratory technique. Histology of kidney was done by standard laboratory procedure. Statistical analysis was done by using SPSS windows Version -16. One way ANOVA and Bonferroni tests were done as applicable. Results: In this study blood glucose level and serum urea level was significantly higher and abnormal histological structure was found in stress induced depressed rats. After taking mushroom extract for 28 days all the parameters were improved. Conclusion: From this study it can be concluded that oyster mushroom(Pleurotus florida) which is excellent edible and nutritious, may have renoprotective effect.

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“…Virgin olive oil, containing monounsaturated fatty acids (MUFAs) and phytochemicals, such as polyphenolic compounds, is an important element in the human diet because of its health benefits [11,12]. MUFAs reduce the circulating lipoprotein's sensitivity to peroxidation because it decreases endothelial activation and the susceptibility of low density lipoprotein (LDL) to oxidation, while phenolic compounds show potent antioxidant properties against lipids, DNA and LDL oxidation; in addition, it has also anti-cancer and anti-inflammatory effects, and ability for immune response modification [13,14]. However, the putative renoprotective effects of virgin olive oil remain to be clarified, namely against CsAinduced nephrotoxicity.…”

Section: Introductionmentioning

confidence: 99%

Renoprotective Effects of Naringenin and Olive Oil against Cyclosporine- Induced Nephrotoxicity in Rats

Elshama

Osman

El-Kenawy

2016

IJT

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Background: Prolonged use of cyclosporine A for prevention of allograft rejection is associated with nephrotoxicity development. Naringenin and olive oil are beneficial dietary antioxidants with potential renoprotective properties. This study aimed to evaluate the therapeutic effect of naringenin and olive oil in alleviating cyclosporine induced nephrotoxicity in rats by the assessment of renal function and lesions, and redox status parameters. Methods: Eighty adult male rats were divided into four groups during a 45 days treatment period; control group received saline; the second group treated with 25 mg/kg/d of cyclosporine while the third and fourth groups received 100 mg/kg/d of naringenin and 1.25 ml/kg/d of virgin olive oil respectively, together with the same cyclosporine dose. Results: Cyclosporine-treated rats presented renal dysfunction and damage, as viewed by the elevated serum markers of renal function and kidney histopathological lesions, when compared to the control animals with an increase in the blood cyclosporine level and impaired redox status parameters. Conclusion: Co-administration of naringenin or virgin olive oil with cyclosporine alleviated nephrotoxicity by serum urea and creatinine levels reduction, renal lesions amelioration, as well as the improved antioxidant parameters. Naringenin and virgin olive oil have potential to act as natural renoprotective agents against cyclosporine-induced nephrotoxicity.

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EFFECT OF VIRGIN OLIVE OIL (<i>OLEA EUROPEA</i>. L) ON KIDNEY FUNCTION IMPAIRMENT AND OXIDATIVE STRESS INDUCED BY MERCURIC CHLORIDE IN RATS

Cited by 14 publications

References 45 publications

Effects of feed supplementation with olive oil on serum testosterone, triiodothyronine, thyroxine and some biochemical metabolites in Teddy goat bucks

Effects of feed supplementation with olive oil on serum testosterone, triiodothyronine, thyroxine and some biochemical metabolites in Teddy goat bucks

Effect of Oyster Mushroom on Kidney in Stress Induced Depressed Rats

Renoprotective Effects of Naringenin and Olive Oil against Cyclosporine- Induced Nephrotoxicity in Rats

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