“…Plasma concentrations of 1,25-DHCC increased during lactation (Perrin, 1955;Harmon et al, 1974Harmon et al, , 1975Mahan and Fetter, 1982;Mahan, 1984;Miller et al, 1994), resulting in an increase of Ca and P absorption from the small intestine. The increased absorption of Ca from the small intestine is mediated through an increased intestinal production of calcium-binding protein (Thomasset et al, 1979), and increased P absorption seems to be a direct effect of 1,25-DHCC on the mucosal surface, which stimulates the entry of phosphate at the mucosal border (Jongbloed, 1987). The effects of 1,25-DHCC on bone resorption are less clear, although it has been shown to be involved, directly or indirectly, in bone mineral turnover.…”