Effect of Wenshentiaojing Decoction on Hormone Level and Follicular Number in Patients with Menstrual Disorder of Polycystic Ovary Syndrome

Abstract

Objective. To explore the curative effect of Wenshentiaojing Decoction on the treatment of menstrual disorder caused by PCOS. Methods. Patients with menstrual disorders caused by PCOS admitted to our department from January 2020 to January 2021 were selected as the research objects and were divided into a control group and observation group according to the random number table method. The control group was treated with Western medicine, and the observation group was treated with Wenshentiaojing Decoction on the basis of Western medicine. The clinical efficacy of the two groups was compared. Before and after treatment, sex hormones (LH, FSH, LH/FSH, and testosterone (T)), ovarian volume, endometrial thickness, cervical mucus score, follicular number, menstrual conditions (menstrual duration, menstrual cycle, and menstrual volume), and other indicators in both groups were recorded. Results. After treatment, the total effective rate of the observation group (91.1% (41/45)) was higher than that of the control group (77.8% (35/45)), and the difference was statistically significant ( P < 0.05 ). After treatment, the LH, LH/FSH, and T levels in the observation group were lower than those in the control group, while the FSH level was higher than that in the control group ( P < 0.05 ). After treatment, the ovarian volume, endometrial thickness, cervical mucus score, and follicle number in the observation group were higher than those in the control group ( P < 0.05 ). After treatment, the menstrual duration and menstrual volume in the observation group were longer than those in the conventional group, and the menstrual cycle was shorter than that in the conventional group ( P < 0.05 ). Conclusion. For patients with menstrual disorders caused by PCOS, the treatment effect of Wenshentiaojing Decoction assisted with Western medicine is better, which can effectively improve the level of sex hormones, cervical mucus, and menstrual conditions, increase the ovarian volume, endometrial thickness, and follicle number, and improve the treatment effect, with fewer adverse reactions, which is worthy of further promotion and application.

Measuring the concentration of some hormones in women with polycystic ovary syndrome

“…[6] showed that the hormone prolactin inhibits the aromatase activity of the ovarian granulosa cells and thus supports the theory of the role of prolactin in suppressing follicular maturation [7]. (Boon., 2006) factor (PIF) It is possible that the increase in the incidence of polycystic ovary syndrome may lead to a state of psychological and neurological disorder in women with this syndrome, and this leads to their suffering from severe anxiety or what is called psychological confinement [8]. (Anxiety), as it is scientifically recognized that the concentration of the hormone prolactin rises significantly in the bloodstream under the influence of stress resulting from deteriorating health and psychological conditions, it was entrusted by [9].…”

Melatonin-Mediated Suppression of mtROS-JNK-FOXO1 Pathway Alleviates Hypoxia-Induced Apoptosis in Porcine Granulosa Cells

“…Ovaries, the primary reproductive organs in female mammals, contain numerous functional units known as ovarian follicles at various stages of development [1]. Abnormal follicle development can lead to long-term anovulation, menstrual disorders, infertility, and an increased risk of endometrial cancer [2]. The follicle consists of a single oocyte surrounded by granulosa cells (GCs).…”