2023
DOI: 10.31557/apjcp.2023.24.5.1687
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Effect of XRCC1 Arg399Gln Gene Polymorphism on Survival in Lymphoblastic Leukemia

Abstract: Introduction: The relevance of the research of the article is conditioned upon the problem of the development of molecular genetic diagnostics to determine the effectiveness of treatment for acute lymphoblastic leukemia in children. The purpose of the article is to identify the polymorphism parameters of the P53 Arg72Pro and XRCC1 Arg399Gln genes in acute lymphoblastic leukemia with criteria for determining the survival rates of sick children. … Show more

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“…Pollutants, radiation, and chemicals are just some of the environmental carcinogens that may play a role. Cancer risk may also be influenced by dietary and lifestyle variables including obesity and inactivity ( Usenova et al, 2023 ). A 40 % of leukemia cases in the West are diagnosed as AML, making it the most common form of acute leukemia in adults.…”
Section: Introductionmentioning
confidence: 99%
“…Pollutants, radiation, and chemicals are just some of the environmental carcinogens that may play a role. Cancer risk may also be influenced by dietary and lifestyle variables including obesity and inactivity ( Usenova et al, 2023 ). A 40 % of leukemia cases in the West are diagnosed as AML, making it the most common form of acute leukemia in adults.…”
Section: Introductionmentioning
confidence: 99%