Effect of Zinc Supplementation on Triglyceride, Cholesterol, LDL, and HDL Levels in Zinc-Deficient Hemodialysis Patients

Roozbeh, Jamshid; Hedayati, Parin; Sagheb, Mohammad Mahdi; Sharifian, Maryam; Jahromi, Alireza Hamidian; Shaabani, Sanaz; Jalaeian, Hamed; Raeisjalali, Ghanbar Ali; Behzadi, S

doi:10.3109/08860220903216055

Cited by 35 publications

(34 citation statements)

References 10 publications

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“…Twenty-two of 35 patients in group A and 21 of 30 patients in group B were zinc deficient (,80 mg/dL). 17 Baseline levels of serum albumin were 3.6 6 0.8 and 3.6 6 0.5 g/dL, and baseline levels of Hb were 9.2 6 2.2 and 9.0 6 2.5 g/dL in group A and B, respectively. Table 1 shows the mean values of serum zinc, TAC, GSH, SOD, and MDA in group A during the placebo (from day 0 to day 160) and zinc supplementation (from day 1120 to day 1180) periods.…”

Section: Resultsmentioning

confidence: 79%

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Effects of Zinc Supplementation on Antioxidant Status and Lipid Peroxidation in Hemodialysis Patients

Mazani

Argani

Rashtchizadeh

et al. 2013

Journal of Renal Nutrition

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Section: Resultsmentioning

confidence: 79%

“…The reference values and cutoff point for zinc deficiency in the Iranian adult population and HD patients were determined by previous studies. 16,17 TAC in serum samples was measured by a spectrophotometry method (CECIL 8000, CECIL Instruments, Cambridge, UK) using a RANDOX TAS kit (RANDOX Laboratories Ltd., Antrim, UK).…”

Section: Methodsmentioning

confidence: 99%

Effects of Zinc Supplementation on Antioxidant Status and Lipid Peroxidation in Hemodialysis Patients

Mazani

Argani

Rashtchizadeh

et al. 2013

Journal of Renal Nutrition

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“…Zinc: La suplencia de zinc en pacientes en hemodiálisis se ha asociado con disminución significativa en los niveles de homocisteína y aumento de colesterol HDL, lo cual mejora el riesgo cardiovascular 22,23 .…”

Section: Erc Con Falla Renalunclassified

Nutritional supplements in chronic kidney disease

Arreaza-Kaufman

Rodríguez

Tassinari

et al. 2016

RCN

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ResumenIntroducción: El estado nutricional de los pacientes con enfermedad renal crónica (ERC) influye sobre el progreso de la enfermedad y se asocia al incremento en el riesgo cardiovascular. Revisamos en la literatura el efecto de los suplementos nutricionales en estos pacientes. Métodos: Se realizó una búsqueda de la literatura en las bases de datos electrónicas Pubmed y Embase para encontrar estudios clínicos que relacionaran el efecto de los suplementos y/o complementos nutricionales con ERC. Resultados: De 353 artículos que resultaron inicialmente, se seleccionaron 26, de los cuales 23 fueron realizados en población con falla renal. En los pacientes con suplencia, se reportaron efectos como disminución en los niveles de homocisteína tras la administración de zinc, omega-3 y ácido fólico. Adicionalmente, se evidenció disminución en los metabolitos de estrés oxidativo. Con la terapia de suplementación con vitamina D se observó mejoría en el perfil lipídico y diminución en hemoglobina glicosilada y PCR. Discusión: Los suplementos y/o complementos nutricionales compuestos por probióticos, ácidos grasos de cadena larga (omega-3), proteí-nas, elementos de traza, antioxidantes y ácido fólico podrían ser de importancia en pacientes con ERC ante los efectos benéficos que han demostrado tener, por la reducción en la homocisteína y otros factores derivados del estrés oxidativo considerados marcadores de riesgo cardiovascular, o también por disminuirse la prevalencia de malnutrición en esta población. Los estudios sugieren que los suplementos y/o complementos nutricionales podrían retrasar el deterioro renal progresivo y reducir los marcadores de riesgo cardiovascular, principalmente en aquellos compuestos por omega-3.Palabras clave: Insuficiencia renal, suplementos dietarios, zinc, ácidos grasos, ácido fólico, proteínas.http://doi.org/10.22265/acnef.3.2.230 Abstract Introduction: The nutritional status of patients with chronic kidney disease (CKD) affects the progress of the disease and is associated with increased cardiovascular risk. We reviewed the literature in search of the effect of nutritional supplements in these patients. Methods: Our search included the electronic databases Pubmed and Embase and was structured to find clinical studies relating the effect of supplements and/or nutritional supplements with CKD. Results: In total the search resulted in 353 articles, 26 were selected, of which 23 were performed in people with kidney failure. In patients with supplements, effects such as decrease in homocysteine levels after administration of zinc, omega-3 and folic acid were reported. Additionally, reduction was observed in the metabolites of oxidative stress. In therapy with vitamin D supplementation resulted in improvements in the lipid profile and reduction in the levels of glycated hemoglobin and PCR. Discussion: Supplements and/or nutritional compliments with compounds probiotics, long chain fatty acids (omega-3), proteins, trace elements, antioxidants and folic acid; Could be relevant in patients with CKD...

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“…Several studies have demonstrated that Zn homeostasis has a critical impact on the health of hemodialysis patients. These patients have significantly lower concentrations of Zn in the blood and leukocytes and have increased oxidative stress (Roozbeh et al, 2009;DashtiKhavidaki et al, 2010). The possible causes of decreased Zn concentrations need to be clarified, although Zn removal during hemodialysis, decreased gastrointestinal absorption of Zn, inadequate Zn intake, and reduced Zn-binding proteins in these patients have been reported.…”

Section: Trace Elementsmentioning

confidence: 99%