Effect on purine releasement of Lentinus edodes by different food processing techniques

Xiao, Lu; Sha, Wanqian; Tao, Chunlin; Hou, Chuanli; Xiao, Ganhong; Ren, Jiaoyan

doi:10.1016/j.fochx.2022.100260

Cited by 8 publications

(8 citation statements)

References 15 publications

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“…According to the relevant literature, hydrochloric acid and calefaction were selected to remove the binding residue, which was a conventional and effective approach used in some analytical methods [ 23 , 27 , 28 , 29 , 30 ]. Focusing on the concentration of hydrochloric acid, heating time, and heating temperature, the optimization of extraction conditions was carried out using the recovery test in 2.0 g of eggplant (1000 µg/kg) and direct analysis after extraction in 8 mL of acetonitrile.…”

Section: Resultsmentioning

confidence: 99%

Development of Acid Hydrolysis-Based UPLC–MS/MS Method for Determination of Alternaria Toxins and Its Application in the Occurrence Assessment in Solanaceous Vegetables and Their Products

Tang

Wang

Fei

et al. 2023

Toxins

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In this work, we proposed an acid hydrolysis-based analytical method for the detection of Alternaria toxins (ATs) in solanaceous vegetables and their products with solid-phase extraction (SPE) and ultrahigh-performance liquid chromatography–tandem mass spectrometry (UPLC–MS/MS). This study was the first to reveal that some compounds in the eggplant matrix bind to altenusin (ALS). Validation under optimal sample preparation conditions showed that the method met the EU criteria, exhibiting good linearity (R2 > 0.99), matrix effects (−66.6–−20.5%), satisfying recovery (72.0–107.4%), acceptable precision (1.5–15.5%), and satisfactory sensitivity (0.05–2 µg/kg for limit of detection, 2–5 µg/kg for limit of quantification). Out of 393 marketed samples, only 47 samples were detected, ranging from 0.54–806 μg/kg. Though the occurrence ratio (2.72%) in solanaceous vegetables could be negligible, the pollution status in solanaceous vegetable products was much more serious, and the incidences were 41.1%. In the 47 contaminated samples, the incidences were 4.26% for alternariol monomethyl ether (AME), 6.38% for alternariol (AOH) and altenuene (ALT), 42.6% for tentoxin (TEN), and 55.3% for tenuazonic acid (TeA).

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Section: Resultsmentioning

confidence: 99%

Development of Acid Hydrolysis-Based UPLC–MS/MS Method for Determination of Alternaria Toxins and Its Application in the Occurrence Assessment in Solanaceous Vegetables and Their Products

Tang

Wang

Fei

et al. 2023

Toxins

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“…Purine is a heterocyclic bicyclic aromatic organic molecule, which includes DNA, RNA, nucleosides and nucleotides, AMP, ADP, ATP, GMP, GDP, GTP, and cyclic forms of cAMP and cGMP, and participates in various metabolic pathways and cell signal transduction ( La Grotta et al, 2022 ; Xiao et al, 2022 ). Uric acid is the product of purine metabolism.…”

Section: Discussionmentioning

confidence: 99%

A Novel Purine and Uric Metabolism Signature Predicting the Prognosis of Hepatocellular Carcinoma

et al. 2022

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Background: Hepatocellular carcinoma (HCC) is regarded as one of the most common cancers in the world with a poor prognosis. Patients with HCC often have abnormal purine and uric acid metabolism, but their relationship with prognosis is unclear.Methods: Here, we collected the data of peripheral blood uric acid and clinical data in 50 patients with HCC and analyzed the relationship with prognosis. At the same time, the transcriptome sequencing data of TCGA and GEO databases were collected to analyze the changes in purine metabolic pathway activity and construct a prognosis prediction model. Based on the prognosis prediction model related to purine metabolism, we further looked for the differences in the immune microenvironment and molecular level and provided possible drug targets.Results: We found that the level of serum uric acid was positively correlated with the prognosis of HCC. At the same time, purine metabolism and purine biosynthesis pathway activities were significantly activated in patients with a poor prognosis of HCC. The prognosis prediction model of HCC based on purine metabolism and purine biosynthesis pathway can accurately evaluate the prognosis of patients with HCC. Meanwhile, we found that there were significant changes in tumor immune infiltration microenvironment and biological function at the molecular level in patients with over-activation of purine metabolism and purine biosynthesis pathway. In addition, we found that uric acid level was positively correlated with peripheral blood leukocytes in HCC patients.Conclusion: In this study, we found that the level of peripheral blood uric acid in patients with HCC is correlated with their prognosis. The prognosis of patients with HCC can be accurately predicted through the metabolic process of uric acid and purine.

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“…The samples were pretreated using a previously reported method (Xiao et al., 2022a). Appropriate amounts of processed beef were sheared into small pieces and collected using 6 mesh and 8 mesh sieves.…”

Section: Methodsmentioning

confidence: 99%

“…The preparation of purine standard solution was according to the method by Xiao et al . (Xiao et al., 2022b).…”

Section: Methodsmentioning

confidence: 99%

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Comparative analysis of food heating techniques on purine release in beef

Tao

Sha

Xiao

et al. 2023

Int J of Food Sci Tech

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Beef is widely believed to be high in purines and should be restricted in the daily diet of hyperuricemia population. In this study, we measured and analysed the purines in beef which treated with several thermal techniques or their combination, including steam heating at 100 °C, 120 °C and 140 °C, microwave heating on low, medium and high fire, and infrared heating at 120 °C, 130 °C and 140 °C. In comparison with raw beef, steam heating at 100 °C (P < 0.0001), high fire microwaved heating (P < 0.0001), and infrared heating at 130 °C (P < 0.0001) reduced the total purine sharply, especially the uricogenic purines. And the superposition of steam heating such as SM (P = 0.002) and SI (P = 0.004) slightly decreased purine contents more than other combinations. Additionally, there were apparent differences in total purines upon the gastrointestinal digestion of processed beef. These provide a viable diet alternative for decreasing the purine contents in beef and which could be essential for managing high uric acid levels for hyperuricemia and gout.

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Effect on purine releasement of Lentinus edodes by different food processing techniques

Cited by 8 publications

References 15 publications

Development of Acid Hydrolysis-Based UPLC–MS/MS Method for Determination of Alternaria Toxins and Its Application in the Occurrence Assessment in Solanaceous Vegetables and Their Products

Development of Acid Hydrolysis-Based UPLC–MS/MS Method for Determination of Alternaria Toxins and Its Application in the Occurrence Assessment in Solanaceous Vegetables and Their Products

A Novel Purine and Uric Metabolism Signature Predicting the Prognosis of Hepatocellular Carcinoma

Comparative analysis of food heating techniques on purine release in beef

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