Effect-site concentration of remifentanil for smooth emergence from propofol-remifentanil anesthesia in patients using double lumen tube

Effect-site concentrations of remifentanil for smooth emergence from combined epidural–general anesthesia or general anesthesia in patients using video double-lumen tube: A randomized trial

“…Lee et al [ 7 ] reported that in female patients under general anesthesia maintained by sevoflurane, the EC 50 and EC 95 values for suppression of cough during DLT extubation were 1.67 ng/ml and 2.28 ng/ml, respectively. In Kang's study of the DLT, the EC 50 was 3.76 ng/ml and the EC 95 was 4.92 ng/ml [ 20 ]. In the present study, the EC 90 for smooth emergence was 3.5 ng/ml in epidural general anesthesia, which was higher than that in general anesthesia (2.7 ng/ml).…”

“…Therefore, the Ce of remifentanil for smooth emergence in patients with a DLT may be different from that in patients with an SLT. In propofol-maintained general anesthesia, the EC 50 values for smooth emergence were 3.76 ng/ml in patients with a DLT [ 20 ] and 1.67 ng/ml in sevoflurane-maintained female patients with a DLT [ 7 ]. These limited reports provide preliminary information and reference for clinical practice, but there are still issues that need to be addressed.…”