2022
DOI: 10.1016/j.microc.2021.107076
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Effective extraction methods based on hydrophobic deep eutectic solvent coupled with functional molecularly imprinted polymers: Application on quercetagetin extraction from natural medicine and blood

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Cited by 18 publications
(8 citation statements)
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“…As the purity of flavonoids from plants is reportedly positively related to their biological activities [ 13 ], it is crucial to establish an efficient method to improve flavonoids purity. At present, many techniques for the enrichment of flavonoids are inefficient and not suitable for large-scale industrial production as they are time- and solvent-consuming, such as ultrafiltration, supercritical fluid extraction, high-speed counter-current chromatography [ 14 ], aqueous two-phase extraction [ 15 ], molecularly imprinted membrane [ 16 ] and preparative HPLC [ 17 , 18 , 19 ]. Because of their relative ideal pore structure, various polarity ranges, high efficiency, environmental friendliness, energy conservation and easy operation, macroporous resins are widely used in flavonoids enrichment from many crude extracts of natural resources such as Pteris ensiformis Burm.…”
Section: Introductionmentioning
confidence: 99%
“…As the purity of flavonoids from plants is reportedly positively related to their biological activities [ 13 ], it is crucial to establish an efficient method to improve flavonoids purity. At present, many techniques for the enrichment of flavonoids are inefficient and not suitable for large-scale industrial production as they are time- and solvent-consuming, such as ultrafiltration, supercritical fluid extraction, high-speed counter-current chromatography [ 14 ], aqueous two-phase extraction [ 15 ], molecularly imprinted membrane [ 16 ] and preparative HPLC [ 17 , 18 , 19 ]. Because of their relative ideal pore structure, various polarity ranges, high efficiency, environmental friendliness, energy conservation and easy operation, macroporous resins are widely used in flavonoids enrichment from many crude extracts of natural resources such as Pteris ensiformis Burm.…”
Section: Introductionmentioning
confidence: 99%
“…The time required to reach adsorption equilibrium (18 min) was shorter than that for traditional MIP. 30 This may be due to the uniform growth of MIPs on the surface of GO/ZIF-67/AgNPs/GCE and the fact that GO/ZIF-67/AgNPs as the substrate made the imprinted cavities exposed to the surface, reducing the encapsulation of template molecules and facilitating the elution and adsorption of p -cresol.…”
Section: Resultsmentioning
confidence: 99%
“…NADES-1 (Choline chloride-Fructose) was found to be the most effective. Several authors have indicated that the percentage of NADES in water has a significant effect on the extraction efficiency, because the viscosity of the resulting NADES solution can vary with the water content [12,13]. Figure 1 shows that when the content of NADES was 85%, the extraction yield decreased, because flavonoids dissolutions and the penetration in the target matrix are limited by the high viscosity [14,15].…”
Section: Evaluation Of Nades Composition On Flavonoid Extraction Effi...mentioning
confidence: 99%