Effective preparation of hexahydroquinolines under ambient and solvent-free conditions

Preparation, characterization and application of novel ionic liquid as an efficient and reusable catalyst for the solvent-free synthesis of hexahydroquinolines

“…Afterwards, the 2-benzylidenedimedone (1) and enamine (2) 60 90 19 2 3 60 49 79 3 5 60 26 84 4 7 60 15 (continued on next page) to the activated carbonyl group. The mechanism is confirmed by the literatures [17,32,33].…”

Novel ionic liquid [2-Eim] HSO4as a dual catalytic-solvent system for preparation of hexahydroquinolines under green conditions

“…All of the desired product(s) were characterized by comparison of their physical and spectral data (melting points, IR, 1 H NMR) with those of known compounds. 15,27,28 2.1.9. Effect of impurity of water on the catalytic activity of 2-ethyl imidazolium hydrogen sulfate.…”

“…All of the desired product(s) were characterized by comparison of their physical and spectral data (melting points, IR, 1 H NMR) with those of known compounds. 15,[27][28] …”

Preparation of neutral ionic liquid [2-Eim] OAc with dual catalytic-solvent system roles for the synthesis of 2-amino-3-cyano-7-hydroxy-4-(aryl)-4H-chromene derivatives

“…In continuation of our previously reported methodologies for designing, synthesis and applications of task specific ionic liquids (TSILs) [32][33][34][35][36][37][38][39][40], herein, the synthesis of novel neutral media ionic liquid 2-ethyl imidazoliumacetate OAc from available and inexpensive starting materials (Scheme 1), and its full characterization by using FT-IR, 1 H NMR, 13 C NMR, UV, TG (thermal gravimetric), DTG (derivative thermal gravimetric), and pH controlling in aqueous media is reported. Afterward, the abovementioned ionic liquid was used as a highly efficient, homogeneous and recyclable catalyst for the preparation of 2-amino-4H-chromene derivatives via the one-pot multi-component condensation of various aldehydes, malononitrile, and resorcinol under thermal solvent-free conditions (Scheme 2).…”