2021
DOI: 10.1080/16078454.2021.1948209
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Effectiveness and safety of romiplostim among patients with newly diagnosed, persistent and chronic ITP in routine clinical practice in central and Eastern Europe: an analysis of the PLATON study

Abstract: Objectives: The objective of this analysis was to assess the effectiveness and safety of romiplostim in the real-world by duration of primary immune thrombocytopenia (ITP): <3 ('newly diagnosed'), 3-12 ('persistent'), and >12 ('chronic') months. Methods: This was a post-hoc analysis of the PLATON single-arm, observational cohort study of adults from five Central and Eastern European countries receiving ≥1 romiplostim dose as second-line therapy, or where surgery was contraindicated. Durable (≥75% of measuremen… Show more

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Cited by 2 publications
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“…ITP is a common hemorrhagic autoimmune disease with an incidence of 2–4/100,000 in adults. 4 ITP can cause asymptomatic thrombocytopenia in mild cases, petechiae and ecchymosis in skin mucosa in severe cases, and even life-threatening visceral bleeding and intracranial hemorrhage, resulting in decreased quality of life. The diagnosis of ITP is made based on the absence of other causes of thrombocytopenia.…”
Section: Discussionmentioning
confidence: 99%
“…ITP is a common hemorrhagic autoimmune disease with an incidence of 2–4/100,000 in adults. 4 ITP can cause asymptomatic thrombocytopenia in mild cases, petechiae and ecchymosis in skin mucosa in severe cases, and even life-threatening visceral bleeding and intracranial hemorrhage, resulting in decreased quality of life. The diagnosis of ITP is made based on the absence of other causes of thrombocytopenia.…”
Section: Discussionmentioning
confidence: 99%