Effectiveness of computed tomography to evaluate central giant cell lesion

Abstract

Central giant cell lesion (CGCL) is a benign disease involving the mandible (70%) more than the maxilla; it tends to be more common in women. Clinically, the lesion may be associated with pain, tooth displacement, facial asymmetry, paraesthesia and ulceration of the mucosa. The radiographic aspect of CGCL is highly variable since it may appear as a unilocular or multilocular radiolucent area with expansion and perforation of the cortical bone. Few previous reports have dealt with the usefulness of CT in the evaluation of this lesion. The purpose of this study is to report the clinical and imaging features of a case, including CT, treated by a conservative method.

Clinical and imagiological findings of central giant cell lesion and cherubism

“…Conventional radiography is generally the first imaging modality performed in clinical practice. However, it offers limited information about cortical integrity, limits and size of the lesion, requiring an exam that offers more details such as CT (1,7). Cortical disruptions and soft tissue involvement can be observed in CT images, and it is useful for defining the limits of the lesion, its components and in determining its dimensions for diagnosis and follow up purposes (7).…”

“…The interpretation of CBCT images must be carefully performed, always considering lesion location, size and development and relation to the adjacent structures as well as enlargement or disruption of the cortical bone (1)(2)(3)(4). With the introduction of CBCT, bone lesions have been more effectively assessed in comparison with conventional radiography, which does not provide details of the lesion and also produces superimposition of images (5)(6)(7)(8)(9)(10)(11). Nevertheless, the use of CBCT is still in discussion, since the radiation dose is higher than for the conventional radiographs.…”

Central Giant Cell Granuloma of the Jaws: A Clinical Study of 17 Cases and a Review of the Literature

“…5 It is obvious that the radiologic and histopathologic features of CGCG are not pathognomonic, so that further clinical and laboratory investigations must be performed to confirm the diagnosis, such as computed tomography (CT) and magnetic resonance imaging (MRI) scans and blood tests (calcium, phosphate, parathyroid hormone, and alkaline phosphatase levels ). 8,[16][17][18][19][20] The purpose of this study was to report and evaluate our experience with the presentation, treatment, and outcome of 17 cases of CGCGs that were treated in the Clinic of Oral and Maxillofacial Surgery at the General Hospital "G. Papanikolaou" in Thessaloniki. We also reviewed the methods of treatment discussed in the literature.…”

Radiotherapy for recurrent central Giant cell granuloma: a case report

“…Non-aggressive lesions do not perforate the cortical bone, and the recurrence rate is low. Aggressive lesions are characterized by rapid growth, perforation of the cortical bone, pain, tooth root resorption, anatomical destruction and dysfunction of involved organs, which results in a high recurrence rate [7, 8]. The primary sites in the present case were the nasal cavity and sinus, which have rarely been reported before.…”