2009
DOI: 10.1007/s11239-009-0352-0
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Effectiveness of enoxaparin for prevention of radial artery occlusion after transradial cardiac catheterization

Abstract: The aim of this study was to assess the efficacy of enoxaparin for prevention of radial artery (RA) occlusion after transradial access for diagnostic and interventional cardiac procedures. RA occlusion is a potential complication of transradial cardiac catheterization. Conventionally, unfractionated heparin is used for prevention of RA occlusion. Effectiveness of low molecular weight heparins for prevention of this complication has not been tested before. Fifty transradial catheterizations were performed for d… Show more

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Cited by 27 publications
(9 citation statements)
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“…Lower body weight, lower systolic blood pressure at haemostasis and the presence of local haematoma and discomfort after the procedure are more frequent findings in radial occlusion 108 . To prevent occlusion, anticoagulation is necessary during the procedure with intravenous unfractionated heparin (UH) 56 or other more costly anticoagulant strategies [113][114][115][116] . Better patency rates are obtained using smaller catheters 115 and careful radial haemostasis techniques, with non-occlusive radial artery compression ideally removed within two hours 5!,118,119 .…”
Section: Complications: Prevention and Managementmentioning
confidence: 99%
“…Lower body weight, lower systolic blood pressure at haemostasis and the presence of local haematoma and discomfort after the procedure are more frequent findings in radial occlusion 108 . To prevent occlusion, anticoagulation is necessary during the procedure with intravenous unfractionated heparin (UH) 56 or other more costly anticoagulant strategies [113][114][115][116] . Better patency rates are obtained using smaller catheters 115 and careful radial haemostasis techniques, with non-occlusive radial artery compression ideally removed within two hours 5!,118,119 .…”
Section: Complications: Prevention and Managementmentioning
confidence: 99%
“…Even patients with normal palmar collateral circulation tests before the transradial procedure can encounter severe ischemic symptoms that warrant treatment. Many physicians apply temporary occlusion of the ulnar artery and anticoagulation in the form of low molecular weight heparin or intravenous heparin injections for recanalization 1 , 11 , 20 , 21 , 36 ). While operative treatment may be required for some patients, RAO is usually asymptomatic.…”
Section: Discussionmentioning
confidence: 99%
“…RAO can preclude radial artery use for access and as a donor for future bypass surgery. The rate of RAO varies from 5% to 30% depending on the tool used for diagnosis, with ultrasound being the most accurate 4 , 11 , 21 , 23 , 26 , 28 - 30 , 36 ). In a large prospective study, Uhlemann et al 30 ) described the advantage of ultrasonography for the investigation of local complications in patients who underwent transradial PCI.…”
Section: Discussionmentioning
confidence: 99%
“…In a study with a group of 39 patients the effect of 60 mg enoxaparin, given to the radial artery sheath, on the occurrence of RAO was evaluated. The incidence of RAO assessed at discharge was low and was 4% [75]. The use of bivalirudin in the prevention of RAO has also been reported.…”
Section: Anticoagulationmentioning
confidence: 99%