Effectiveness of Long-Acting Terramycin Injectable Solution in the Treatment of Streptothricosis in Cattle

Ogwu, D.; Alhaji, I.; Osori, D.I.K.

doi:10.1016/s0007-1935(17)31535-x

Cited by 11 publications

(9 citation statements)

References 3 publications

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“…Changes in these constituents are often associated with disease and might be good laboratory markers for diagnosis and disease surveillance (20). The present study confirmed the potential to treat dermatophilosis effectively, as reported by previous studies (5,10,15,17). Recovery was noted among dermatophilosis cases that were caught early or in cattle that were only mildly affected.…”

Section: Discussionsupporting

confidence: 91%

“…The required dose of gentamycin for adult cattle was expensive, in comparison with long-acting oxytetracycline and the combination of penicillin and streptomycin. In this way, the study confirms previous findings which recommend long-acting oxytetracycline and the penicillinstreptomycin combination (5,10,15,17,20). Furthermore, a better treatment -the gentamycin -has emerged.…”

Section: Discussionsupporting

confidence: 91%

“…However, due to the short duration of this combination, long-acting oxytetracycline was tried (10,15). Ogwu et al (17) found no difference in bacteriological criteria. Four types of treatment were chosen on the basis of recent in vitro testing results (16).…”

Section: Introductionmentioning

confidence: 93%

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The treatment of bovine dermatophilosis and its effect on some haematological and blood chemical parameters

Hamid

Musa²

2009

Rev. Sci. Tech. OIE

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In this study, the authors evaluated parenteral treatment of zebu cattle, with naturally and experimentally induced bovine dermatophilosis, in western Sudan, using four different antibiotic treatments. In terms of recovery rate, weight gain, avoiding relapse and preventing death, gentamycin was found to be the most effective treatment, followed by a combination of penicillin and streptomycin and, finally, long-acting oxytetracycline. However, enrofloxacin was not successful. A significant improvement in the red blood cell count was noticed among cattle treated with penicillin-streptomycin (p = 0.021) and gentamycin (p = 0.029). All treated cattle, except those treated with enrofloxacin, showed a significant improvement in mean corpuscular haemoglobin concentration (p = 0.021); mean corpuscular volume (p = 0.021), and white blood cell count (p < 0.021). Significant improvements were observed among treated cattle in their total levels of protein, calcium (p = 0.021) and cholesterol (p < 0.05), when compared to untreated cattle infected with Dermatophilus congolensis. This study recommends gentamycin as a drug of choice for the parenteral treatment of dermatophilosis. Treatment was not only effective in early, mild cases but also useful among moderately and heavily affected cattle. According to the observations of the authors, when no intervention took place, the condition of moderately and heavily affected cattle deteriorated and/or resulted in death. Keywords Antibiotics-Bovine dermatophilosis-Cutaneous streptothricosis-Dermatophilus congolensis-Haematological and blood chemical parameters-Sudan-Western Sudan-Zebu cattle.

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Section: Discussionsupporting

confidence: 91%

Section: Discussionsupporting

confidence: 91%

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The treatment of bovine dermatophilosis and its effect on some haematological and blood chemical parameters

Hamid

Musa²

2009

Rev. Sci. Tech. OIE

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“…While some workers (Ilemobade et al, 1979;Lloyd et al, 1990) found that a single injection of L]AO was effective even if it did not give 100% recovery rate, Ogwu et al (1981) did not achieve appreciable results. Long-acting oxytetracycline (L/AO) is widely used.…”

Section: Introductionmentioning

confidence: 99%

Chemotherapy of dermatophilosis—A preliminary study

Aning¹,

Koney

1996

Trop Anim Health Prod

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In view of the unpredictability of results of antibiotic therapy of bovine dermatophilasis and following the report of successful use of 10% formalin administered intravenously at the dosage of 20ml per lOOkg body weight, a trial was undertaken to evaluate the latter treatment in naturally-occurring dermatophilosis in a group of Friesian crossbred cattle. Group 1 animals were given only 10% formalin. Group 2 received 10% formalin and long-acting oxytetracycline (L/AO) at a dosage of 20mg per kg body weight and Group 3 animals were given only L/AO. Treatments were repeated at intervals of four days. All animals recovered fully, the formalin only-treated ones after three treatments the L/AO-treated ones after a mean of 2"7 treatments and the combination-treated animals after a mean of 1"5 treatments. One LA/O-treated animal showed relapse after four months. This study is continuing.

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“…Ainsi selon Ogwu et coll. (17), la terramycine longue action n'entraîne pas une guérison complète de la maladie et, d'après Lloyd et coll. (13), l'oxytétracycline longue action ne fait que diminuer la fréquence des récidives.…”

Section: ■ Introductionunclassified

Activités antibactériennes in vitro de Cassia alata, Lantana camara et Mitracarpus scaber sur Dermatophilus congolensis isolé au Bénin

Ali

Moudachirou

Akakpo

et al. 2002

Rev. Elev. Med. Vet. Pays Trop.

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L’activité antibactérienne in vitro des extraits aqueux et alcooliques de Cassia alata, de Lantana camara et de Mitracarpus scaber a été comparée avec celle de l’oxytétracycline et de la pénicilline procaïne sur une bactérie Gram-positif, Dermatophilus congolensis, agent de la dermatophilose bovine. Les extraits alcooliques bruts de C. alata, de L. camara et de M. scaber se sont révélés plus actifs sur D. congolensis que leurs extraits aqueux. Les zones d’inhibition à 500 mg/ml ont été de 14 à 20 mm et de 20 à 24 mm respectivement pour les extraits aqueux et alcooliques sur une souche isolée d’animaux infectés. Les deux extraits de M. scaber ont montré une activité antibactérienne plus élevée sur D. congolensis que ceux de C. alata et de L. camara. L’activité antibactérienne des extraits alcooliques bruts de M. scaber in vitro sur D. congolensis, à 500 mg/ml, a été équivalente à celle de la pénicilline procaïne à la concentration de 800 mg/ml et environ 10 à 15 fois moindre que celle de l’oxytétracycline.

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Effectiveness of Long-Acting Terramycin Injectable Solution in the Treatment of Streptothricosis in Cattle

Cited by 11 publications

References 3 publications

The treatment of bovine dermatophilosis and its effect on some haematological and blood chemical parameters

The treatment of bovine dermatophilosis and its effect on some haematological and blood chemical parameters

Chemotherapy of dermatophilosis—A preliminary study

Activités antibactériennes <em>in vitro</em> de <em>Cassia alata, Lantana camara</em> et <em>Mitracarpus scaber</em> sur <em>Dermatophilus congolensis</em> isolé au Bénin

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