Effectiveness of medical management in Adenomyosis

Abstract

Introduction: Adenomyosis is defined by the abnormal location of endometrial tissue within the myometrium associated with hypertrophy or hyperplasia of the myometrial stroma. It is a chronic estrogen dependent condition. Although pathogenesis and etiology of adenomyosis remain unknown, two main theories have been proposed: invagination of the endometrial basal layer and metaplasia of embryonic stem cells. Prevalence of adenomyosis varies widely from 5 to 70% with recent studies showing about 20% prevalence among which the majority were premenopausal. Materials and Methods: A Comparative Study was conducted from March 2022-August 2022. Women attending Gynec OPD with Abnormal Uterine bleeding due to Adenomyosis confirmed by sonography at Vinayaka Mission’s Kiruparananda Variyar Medical College and Hospital, Salem. Patients coming to Gynecology OPD with complaints of heavy menstrual bleeding, confirmed diagnosis of adenomyosis by ultrasonography, fulfilling the criteria and ready to followup to be enrolled in the study. A detailed history to be obtained with regard to age, parity, age of menarche, time since bleeding starts, duration and frequency of menstrual cycle.