The recent trend of Pesticide use is accelerating for agricultural production purposes. Its importance is immense for controlling pests in developing countries like Bangladesh. But the imprudent application is increasing at an alarming rate due to which environmental degradation is increasing, which is not still under investigation. Despite the various pest control methods, chemical pesticides (hereafter pesticides) are more popular among Bangladeshi farmers because of their low cost and rapid action. The continuous popularity of pesticides application adversely affects the environment, and eventually, human throughout the country. Hence a systematic review was initiated utilizing the secondary information to overview the hazardous impact or prevailed pollution due to the application of pesticides in the context of the environment, related organisms, and human health. The analysis revealed that pollution-related problem arises mostly due to the unregulated use of pesticides. Therefore, excessive pesticide usage such as pollutes the air, soil, and water and kills non-target organisms, causing an ecological imbalance. Lack of protection exposes farmers to acute illnesses, toxic compounds in the food cycle, and the mass population to chronic health issues. Thus, to minimize pesticides' environmental, and health effects, concerns should be given on the judicious application of pesticides, raising awareness regarding pesticide use. Policymakers should focus on raising awareness regarding the use of pesticides, implementing effective pesticide usage laws at the root level, optimizing reasonable use, participatory program implementation for farmers' training, good governance and regulatory mechanisms, frequent inspection at the field level, and appropriate actions and strategies for promoting eco-friendly methods.