Pérez-Ifrán, P, Magallanes, CA, de S. Castro, FA, Astorino, TA, and Benítez-Flores, S. Extremely low-volume burpee interval training equivalent to 8 minutes per session improves vertical jump compared with sprint interval training in real-world circumstances. J Strength Cond Res XX(X): 000–000, 2023—The aim of this study was to compare the cardiometabolic and physical effects of 2 time-matched high-intensity programs in a real-world environment. Forty-three active and healthy adults (sex = 31 men and 12 women; age = 27 ± 5 years; peak heart rate [HRpeak] = 190.7 ± 10.6 beat·min−1) were randomized to 2 very low-volume protocols (∼8 minutes): sprint interval training (SIT) (n = 15), burpee interval training (BIT) (n = 15), and control (CON) (n = 13). Subjects in SIT and BIT performed 5 days of 10 × 4 second “all-out” efforts with 30 seconds of recovery. Body composition, blood pressure, countermovement jump (CMJ), 10-m sprint, shuttle run test (SRT), autonomic modulation, self-efficacy, and intention were evaluated before and after training. Sprint interval training elicited a higher %HRpeak, energy expenditure, rating of perceived exertion category ratio 10 scale, and feeling scale than BIT (p < 0.05). SRTdistance was significantly improved in SIT (p = 0.03, d = 0.62), whereas CMJ height was significantly enhanced in BIT (p = 0.0014, d = 0.72). Self-efficacy progressively worsened for SIT than for BIT as sessions increased, and significant differences were found in 5× a week frequency between protocols (p = 0.040, d = 0.79). No differences in intention to engage were detected between the regimens (p > 0.05). No changes were observed in body composition, blood pressure, 10-m sprint, SRTV̇O2max, or autonomic variables with training (p > 0.05). Results exhibit that extremely low-volume SIT improved running performance, whereas BIT increased the vertical jump.