Effects of 4-week continuous ingestion of champignon extract on halitosis and body and fecal odor

Abstract

This was placebo-controlled double-blind parallel-group comparative clinical trial targeting 80 men and women aged 50–79 years with halitosis and body and fecal odor. We investigated whether daily champignon extract ingestion for 4 weeks improved these conditions. Subjects were divided into four groups: a placebo group and 50, 500, and 1000 mg/day ingestion groups. No severe adverse events or side effects were noted during the study period. Compared with the placebo group, all champignon extract ingestion groups showed improvement or tendency toward improvement in halitosis and body and fecal odor. Furthermore, our results suggested that the effectiveness of champignon extract in alleviating odors is dose-dependent, i.e., it increases with the dosage.

Effects of 4-week continuous ingestion of champignon extract on bowel movements and intestinal putrefaction products: a randomized, placebo-controlled, double-blinded, parallel-group comparative trial

“…In a previous study, we demonstrated improvements in stool color, sense of complete evacuation of stool, and stool odor [11], in which stool odor significantly decreased after 4 weeks in all the test groups (50, 500, and 1000 mg/day) compared with the placebo group. This report is consistent with the current results shown in this study.…”

“…The colon environment also improved, resulting in the increase of the number of days with bowel movement, number of bowel movements, and stool volumes. As the previous study [11] was a trial on healthy subjects, no subject had outlier values for any of the data associated with bowel movement (number of days with bowel movement, number of bowel movements, and stool volumes). As a result, the improvement in parameters indicating bowel movement in the test group was not conclusive, as the subjects who ingested the champignon extract already had regular, healthy bowel movement.…”

“…Ingesting champignon extract for 4 consecutive weeks at 50, 500, and 1000 mg/day significantly decreased halitosis and body and fecal odor compared with the placebo group. The evaluation was conducted using the visual analog scale, with significant differences among the test groups [11].…”

“…This study analyzed the feces collected from subjects who participated in the previous study [11] which examined the effects of champignon extract on the levels of fecal putrefaction products, such as ammonia, p-cresol, and indole between the test and placebo groups.…”

A Current Approach to Halitosis and Oral Malodor- A Mini Review

“…In another study, it was demonstrated that champignon extract made improvement in halitosis and body odor. It is stated that the effectiveness of champignon extract increases with the dosage [ 32 ]. Probiotics have also been shown to be beneficial in reducing bacterial populations in halitosis and periodontitis [ 33 ].…”