2011
DOI: 10.1507/endocrj.ej11-0036
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Effects of a novel short-term continuous subcutaneous insulin infusion program evaluated by continuous glucose monitoring on young adult type 1 diabetic patients in Taiwan

Abstract: Glycemic control in young type 1 diabetic patients is a mission that usually perturbs the clinicians. The frequently encountered physical (body composition and hormonal variations), environmental stress (challenges due to family, society, work, and friends) and emotional factors affect insulin requirements of the individuals. Glucose fluctuation, hypoglycemia and weight gain are difficult to avoid during multiple daily injections (MDI) of insulin treatment [1].Continuous subcutaneous insulin infusion (CSII), w… Show more

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Cited by 7 publications
(18 citation statements)
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“…In this study, the basal insulin accounted for less than 40% of total daily insulin dose. A smaller proportion of basal insulin during CSII among Asian versus Western populations was also documented in our previous study of young adult patients with T1D [ 3 ]. Some other report had revealed the lower basal to total daily dose ratio in Japanese T1D whose food was similar to Taiwanese.…”
Section: Discussionsupporting
confidence: 68%
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“…In this study, the basal insulin accounted for less than 40% of total daily insulin dose. A smaller proportion of basal insulin during CSII among Asian versus Western populations was also documented in our previous study of young adult patients with T1D [ 3 ]. Some other report had revealed the lower basal to total daily dose ratio in Japanese T1D whose food was similar to Taiwanese.…”
Section: Discussionsupporting
confidence: 68%
“…We analyzed data from a total of 45 type 1 diabetic patients receiving CSII therapy at the Department of Pediatrics of Chang Gung Memorial Hospital between 2004 and 2012. In order to be included in the current study, participants had to meet all the following criteria: (a) very low C-peptide level (<0.35 ng/mL) [ 3 , 6 ] with or without the presence of diabetic ketoacidosis, (b) pump-naïve, and (c) ambulatory and willing to cooperate during the program. Patients were treated with multiple daily injections of insulin glargine (Sanofi Aventis) or detemir (Novo Nordisk) as basal and insulin aspart (Novo Nordisk) as bolus at least three times daily.…”
Section: Methodsmentioning
confidence: 99%
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“…Postprandial blood glucose levels and the percentage of time in hypo‐ or hyperglycemia represent variations in impaired fasting glycemia (24), and patients with abnormal 24 h MBG and percentage of time in hypoglycemia may be in an early stage of prediabetes. The extensive data from CGM are able to characterize blood glucose profiles in prediabetes, as well as in patients with type 1 diabetes mellitus (45) and T2DM (46). Thus, the CGMS may be able to detect abnormal glucose metabolism in PCOS patients earlier and more accurately than OGTT, which is presently used to screen patients for abnormal glucose metabolism.…”
Section: Discussionmentioning
confidence: 99%