Effects of a six-month yoga intervention on the immune-inflammatory pathway in antipsychotic-stabilized schizophrenia patients: A randomized controlled trial

Mullapudi, Thrinath; Debnath, Monojit; Govindaraj, Ramajayam; Palanimuthu, Vasanth Raj; Banerjee, Moinak; Varambally, Shivarama

doi:10.1016/j.ajp.2023.103636

Cited by 8 publications

(3 citation statements)

References 63 publications

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“…After screening, a total of 25 articles were finally included 28 , 38 – 61 , and Table 1 displays the characteristics of the included studies. The publication years of the included studies ranged from 2007 to 2023.…”

Section: Resultsmentioning

confidence: 99%

Comparative efficacy of different types of exercise modalities on psychiatric symptomatology in patients with schizophrenia: a systematic review with network meta-analysis

Cui,

Liu,

Liang

et al. 2024

Sci Rep

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This network meta-analysis investigated the effects of 8 types of physical exercises on treating positive symptoms, negative symptoms, general psychopathology, and the Positive And Negative Syndrome Scale (PANSS) total score in patients with schizophrenia. The methods adhered to PRISMA guidelines and used the Cochrane risk of bias tool for quality assessment, and Stata software for data analysis. Data were sourced from PubMed, Embase, Web of Science, and the Cochrane database up to August 15, 2023, following PICOS principles. A total of 25 studies including 1441 participants were analyzed. Results showed that resistance exercise seems to be effective for improving positive symptoms, while Yoga was more effective for negative symptoms. Low-intensity aerobic exercise was optimal for general psychopathology, and Yoga was effective in improving the PANSS total score. The study concluded that yoga and aerobic exercise demonstrated superior performance, but the impact of exercise on patients with schizophrenia is also influenced by individual factors and intervention dosages. Therefore, a pre-assessment of patients considering factors such as interests, hobbies, and physical capabilities is crucial for selecting appropriate exercise modalities.

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Section: Resultsmentioning

confidence: 99%

Comparative efficacy of different types of exercise modalities on psychiatric symptomatology in patients with schizophrenia: a systematic review with network meta-analysis

Cui,

Liu,

Liang

et al. 2024

Sci Rep

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“…This approach is used to modulate pain, increasing the release of adenosine, which is an endogenous anti-nociceptive molecule. Neuroimaging studies with functional magnetic resonance revealed that acupuncture can modulate limbic areas involved in affective pain, also activating anti-nociceptive brain areas like PAG [98,99].…”

Section: Physical Approachesmentioning

confidence: 99%

Psycho-Neuroendocrinology in the Rehabilitation Field: Focus on the Complex Interplay between Stress and Pain

Bonanno,

Papa,

Cerasa

et al. 2024

Medicina

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Chronic stress and chronic pain share neuro-anatomical, endocrinological, and biological features. However, stress prepares the body for challenging situations or mitigates tissue damage, while pain is an unpleasant sensation due to nociceptive receptor stimulation. When pain is chronic, it might lead to an allostatic overload in the body and brain due to the chronic dysregulation of the physiological systems that are normally involved in adapting to environmental challenges. Managing stress and chronic pain (CP) in neurorehabilitation presents a significant challenge for healthcare professionals and researchers, as there is no definitive and effective solution for these issues. Patients suffering from neurological disorders often complain of CP, which significantly reduces their quality of life. The aim of this narrative review is to examine the correlation between stress and pain and their potential negative impact on the rehabilitation process. Moreover, we described the most relevant interventions used to manage stress and pain in the neurological population. In conclusion, this review sheds light on the connection between chronic stress and chronic pain and their impact on the neurorehabilitation pathway. Our results emphasize the need for tailored rehabilitation protocols to effectively manage pain, improve treatment adherence, and ensure comprehensive patient care.

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“…At the molecular level, studies indicate yoga and tai chi increase anti-inflammatory cytokines like IL-10 and IL-4, while reducing pro-inflammatory cytokines such as TNF-α, IL-6, and IL-1β [ 242 , 243 ]. These effects help counteract chronic inflammatory processes underlying chronic pain conditions.…”

Section: Types Of Ninptmentioning

confidence: 99%

Multimodal non-invasive non-pharmacological therapies for chronic pain: mechanisms and progress

Shi,

2023

BMC Med

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Background Chronic pain conditions impose significant burdens worldwide. Pharmacological treatments like opioids have limitations. Non-invasive non-pharmacological therapies (NINPT) encompass diverse interventions including physical, psychological, complementary and alternative approaches, and other innovative techniques that provide analgesic options for chronic pain without medications. Main body This review elucidates the mechanisms of major NINPT modalities and synthesizes evidence for their clinical potential across chronic pain populations. NINPT leverages peripheral, spinal, and supraspinal mechanisms to restore normal pain processing and limit central sensitization. However, heterogeneity in treatment protocols and individual responses warrants optimization through precision medicine approaches. Conclusion Future adoption of NINPT requires addressing limitations in standardization and accessibility as well as synergistic combination with emerging therapies. Overall, this review highlights the promise of NINPT as a valuable complementary option ready for integration into contemporary pain medicine paradigms to improve patient care and outcomes.

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Effects of a six-month yoga intervention on the immune-inflammatory pathway in antipsychotic-stabilized schizophrenia patients: A randomized controlled trial

Cited by 8 publications

References 63 publications

Comparative efficacy of different types of exercise modalities on psychiatric symptomatology in patients with schizophrenia: a systematic review with network meta-analysis

Comparative efficacy of different types of exercise modalities on psychiatric symptomatology in patients with schizophrenia: a systematic review with network meta-analysis

Psycho-Neuroendocrinology in the Rehabilitation Field: Focus on the Complex Interplay between Stress and Pain

Multimodal non-invasive non-pharmacological therapies for chronic pain: mechanisms and progress

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