2014
DOI: 10.4103/0973-8258.129579
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Effects of Adhatoda vasica leaf extract in depression co-morbid with alloxan-induced diabetes in mice

Abstract: Context: Increased neuronal oxidative stress as a consequence of diabetes may result in neuropsychological complications such as depression. Depression co-morbid with diabetes further hampers the quality life years in diabetic patients. Aim: Thus, the present study was aimed at investigating the effects of Adhatoda vasica leaf extract (EAV), as a natural remedy, in alloxan-induced diabetes and co-morbid depression in mice. Materials and Methods: Experimentally, mice were rendered diabetic with a single dose of… Show more

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Cited by 6 publications
(2 citation statements)
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“…It not only lowers blood glucose levels but also reverses diabetes-related depression when compared to escitalopram. (48). Vasaka can be employed as anti-diabetic either as a plant source, the active constituent, herbal formulation, or most importantly, nanoformulation.…”
Section: Anti-diabetic Activitymentioning
confidence: 99%
“…It not only lowers blood glucose levels but also reverses diabetes-related depression when compared to escitalopram. (48). Vasaka can be employed as anti-diabetic either as a plant source, the active constituent, herbal formulation, or most importantly, nanoformulation.…”
Section: Anti-diabetic Activitymentioning
confidence: 99%
“…Guduchi stem is well known for its immune system-stimulating properties as well as for the treatment of elevated blood sugar levels [48,49]. Vasaka is known for its antidiabetic activities [50,51], while wheatgrass [52,53], which is also anti-hyperglycemic and hypolipidemic, contains nutrients and vitality that assist cure in many conditions.…”
Section: Interventions For Each Groupmentioning
confidence: 99%