2005
DOI: 10.1016/j.fct.2005.01.004
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Effects of aflatoxin B1 on embryo fetal development in rabbits

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Cited by 69 publications
(55 citation statements)
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“…In addition to the above effects, aflatoxins have been shown to contribute to reduced birth weight and teratogenic effects in livestock such as pigs and rabbits (Wangikar et al 2005). Regarding the effect on male reproduction, aflatoxins may reduce sperm quality and fertility for roosters, bulls, mice, and rabbits (Hafez, Megalla, and Mahmed 1982;Hafez et al 1983;Ortatatli et al 2002;Fapohunda et al 2008).…”
Section: Impact On Livestock Productivitymentioning
confidence: 99%
“…In addition to the above effects, aflatoxins have been shown to contribute to reduced birth weight and teratogenic effects in livestock such as pigs and rabbits (Wangikar et al 2005). Regarding the effect on male reproduction, aflatoxins may reduce sperm quality and fertility for roosters, bulls, mice, and rabbits (Hafez, Megalla, and Mahmed 1982;Hafez et al 1983;Ortatatli et al 2002;Fapohunda et al 2008).…”
Section: Impact On Livestock Productivitymentioning
confidence: 99%
“…Rabbit is considered as one of the most suitable and sensitive animal model for studying the teratogenic potential of a chemical (World Health Organization, 1993). Wangikar et al (2005) showed that AFB 1 was found to be teratogenic in rabbits when given by oral route during gestation days 6-18 and the dose of 0.1 mg/kg could be considered as the minimum oral teratogenic dose. In this study the mean fetal weights were significantly reduced and the gross anomalies observed included wrist drop and enlarged eye socket whereas, skeletal anomalies were agenesis of caudal vertebrae, incomplete ossification of skull bones and bent metacarpals.…”
Section: Mechanisms Of Toxicity In Petsmentioning
confidence: 99%
“…AFB 1 toxicity also caused damage to other tissues, such as the kidney, testicles, brain and thyroids (Lakkawar et al, 2004). The teratogenic effects of AFB 1 on rabbits were described as enlarged eye sockets and enlarged fetal livers (Wangikar et al, 2005a) and the dose of 0.1 mg/kg BW was considered to be the minimum oral teratogenic dose (Wangikar et al, 2005b).…”
Section: Aflatoxinsmentioning
confidence: 99%