Effects of air polishing and an amino acid buffered hypochlorite solution to dentin surfaces and periodontal ligament cell survival, attachment, and spreading

Schmidlin, Patrick R.; Fujioka‐Kobayashi, Masako; Mueller, Heinz-Dieter; Sculean, Anton; Lussi, Adrian; Miron, Richard J.

doi:10.1007/s00784-016-1950-9

Cited by 10 publications

(13 citation statements)

References 33 publications

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“…An important aspect that needs to be discussed is that despite the fact that at 6 months after therapy, a dramatic reduction in the percentages of sites with PD ≥ 5 mm was measured in both groups; the magnitude of the improvement was statistically significantly higher when NaOCl gel was also applied. These clinical results appear to support the findings from "in vitro" studies which have provided evidence for the antibacterial effect of this novel NaOCl formulation and its positive effects on the survival, attachment and spreading of periodontal ligament cells [14,15].…”

Section: Discussionsupporting

confidence: 81%

Changes in clinical parameters following adjunctive local sodium hypochlorite gel in minimally invasive nonsurgical therapy (MINST) of periodontal pockets: a 6-month randomized controlled clinical trial

et al. 2021

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Background The mechanical disruption and removal of the subgingival biofilm represent the most important step in the treatment of periodontitis. However, in deep periodontal pockets, mechanical removal of the subgingival biofilm is difficult and frequently incomplete. Preliminary findings indicate that the use of amino acid buffered sodium hypochlorite (NaOCl) gel may chemically destroy the bacterial biofilm and facilitate its mechanical removal. Objectives To clinically evaluate the efficacy of minimally invasive nonsurgical therapy (MINST) of periodontal pockets with or without local application of an amino acid buffered sodium hypochlorite (NaOCl) gel. Materials and methods Forty untreated patients diagnosed with severe/advanced periodontitis (i.e. stage III/IV) with a slow/moderate rate of progression (i.e. grade A/B) were randomly allocated in two treatment groups. In the test group, the periodontal pockets were treated by means of MINST and NaOCl gel application, while in the control group, treatment consisted of MINST alone. Full-mouth plaque scores (FMPS), full-mouth bleeding scores (FMBS), probing depths (PD), clinical attachment levels (CAL) and gingival recessions (GR) were assessed at baseline and at 6 months following therapy. The primary outcome variable was PD reduction at sites with PD ≥ 5 mm at baseline. Results At 6 months, statistically significant differences between the two groups were found (p = 0.001) in terms of PD and CAL change. No statistically significant differences were found in terms of GR (p = 0.81). The number of sites with PD ≥ 5 mm and BOP (+) decreased statistically significantly (p = 0.001), i.e. from 85.3 to 2.2% in the test group and from 81.6 to 7.3% in the control group, respectively. Statistically significant differences between test and control groups were recorded at 6 months (p = 0.001). MINST + NaOCl compared to MINST alone decreased statistically significantly (p = 0.001) the probability of residual PDs ≥ 5 mm with BOP− (14.5% vs 18.3%) and BOP+ (2.2% vs. 7.2%). Conclusions Within their limits, the present results indicate that (a) the use of MINST may represent a clinically valuable approach for nonsurgical therapy and (b) the application of NaOCl gel in conjunction with MINST may additionally improve the clinical outcomes compared to the use of MINST alone. Clinical relevance In patients with untreated periodontitis, treatment of deep pockets by means of MINST in conjunction with a NaOCl gel may represent a valuable approach to additionally improve the clinical outcomes obtained with MINST alone

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Section: Discussionsupporting

confidence: 81%

Changes in clinical parameters following adjunctive local sodium hypochlorite gel in minimally invasive nonsurgical therapy (MINST) of periodontal pockets: a 6-month randomized controlled clinical trial

et al. 2021

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“…An enhanced cell attachment could be also caused by erythritol. This assumption is supported by an observation, that spreading of periodontal cells on erythritol‐treated dentin was somewhat higher compared to untreated controls (Schmidlin et al., ).…”

Section: Discussionmentioning

confidence: 65%

Osteoblast growth, after cleaning of biofilm‐covered titanium discs with air‐polishing and cold plasma

Matthes

Duske

Kebede

et al. 2017

J Clinic Periodontology

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“…These osteoconductive particles may have compensated the adverse effects of endotoxin and previous contamination. AA with erythritol also improved osteoblast‐like cell proliferation probably due to improved cell spreading . For the fibroblast cells, the one study that evaluated cell proliferation showed that cell viability on pristine samples equaled those following AA with SB.…”

Section: Discussionmentioning

confidence: 99%

“…AA with erythritol also improved osteoblast-like cell proliferation 60,84 probably due to improved cell spreading. 103 For the fibroblast cells, the one study that evaluated cell proliferation showed that cell viability on pristine samples equaled those following AA with SB. Besides the ablation potential of SB, this result can be due to the fact that this study used one bacterial species (Porphyromonas gingivalis) instead of complex biofilm.…”

Section: Contaminated Surfacesmentioning

confidence: 99%

Effects of air abrasive decontamination on titanium surfaces: A systematic review of in vitro studies

Moharrami¹,

Perrotti

Iaculli

et al. 2019

Clin Implant Dent Rel Res

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Background Air abrasion (AA) is one of the decontamination methods that have demonstrated promising results in treating peri‐implant diseases. Purpose This systematic review aimed at evaluating the in vitro effect of AA on surface change, cleaning efficacy, and biocompatibility of titanium surfaces and at comparing it with other decontamination methods. Materials and Methods A comprehensive search was conducted up to April 2018 using PubMed, Scopus, and Google Scholar databases to identify studies on the decontamination effect of AA. All types of titanium surfaces, abrasive powders, contaminated surfaces, and measuring methods were included. Results Overall, 1502 articles were identified. After screening the titles and abstracts, and carefully reading the full‐texts, 48 articles published between 1989 and 2018 were selected. AA was considered almost safe, particularly for the nonmodified surfaces. Nevertheless, harder powders such as sodium bicarbonate tended to damage the surface more than glycine. AA resulted in surface change similar to plastic curettes and Er: YAG lasers. Regarding the cleaning efficacy, there was no significant difference between glycine and sodium bicarbonate, but different mixtures of calcium phosphate, hydroxyapatite, and erythritol were superior to glycine. AA was superior or equal to all other decontamination methods in cleaning. Regarding biocompatibility, AA was more successful in preserving biocompatibility for noncontaminated surfaces compared with contaminated surfaces and when used with erythritol and osteoinductive powders. Conclusions AA can efficiently remove contamination without serious damage to the surface. The main drawback of the AA method seems to be its limitation in restoring the biocompatibility of the surface.

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Effects of air polishing and an amino acid buffered hypochlorite solution to dentin surfaces and periodontal ligament cell survival, attachment, and spreading

Abstract: The use of air polishing or application with Perisolv amino acid buffered hypochlorite solution was effective in treating root surfaces and allowed for near 100 % PDL cell survival, attachment, and spreading onto all root surfaces.

Cited by 10 publications

References 33 publications

Changes in clinical parameters following adjunctive local sodium hypochlorite gel in minimally invasive nonsurgical therapy (MINST) of periodontal pockets: a 6-month randomized controlled clinical trial

Changes in clinical parameters following adjunctive local sodium hypochlorite gel in minimally invasive nonsurgical therapy (MINST) of periodontal pockets: a 6-month randomized controlled clinical trial

Osteoblast growth, after cleaning of biofilm‐covered titanium discs with air‐polishing and cold plasma

Effects of air abrasive decontamination on titanium surfaces: A systematic review of in vitro studies

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