2022
DOI: 10.1186/s12890-022-02238-x
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Effects of airway pressure release ventilation on multi-organ injuries in severe acute respiratory distress syndrome pig models

Abstract: Background Extra-pulmonary multi-organ failure in patients with severe acute respiratory distress syndrome (ARDS) is a major cause of high mortality. Our purpose is to assess whether airway pressure release ventilation (APRV) causes more multi-organ damage than low tidal volume ventilation (LTV). Methods Twenty one pigs were randomized into control group (n = 3), ARDS group (n = 3), LTV group (n = 8) and APRV group (n = 7). Severe ARDS model was in… Show more

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