Effects of Amygdaloid Lesions on Hypothalamic--Hypophysial Luteinizing Hormone Activity

The Role of the Medial and Central Amygdala in Stress-Induced Suppression of Pulsatile LH Secretion in Female Rats

“…Conversely, MeA lesioning has also been shown to reduce ovulation (12) and the mating-induced enhancement of lordosis in female rats (41). Furthermore, the precise role of the MeA in the control of LH secretion is also controversial with reports of increases in LH secretion after both MeA lesioning (17) and MeA stimulation in rats (13, 42, 43) and reports indicating that MeA lesioning has no effect on LH secretion in the rhesus monkey (44), immature rat (45), and deer-mice (46). Nonetheless the studies presented above, regardless of whether they demonstrate an inhibitory or stimulatory role for the MeA on LH secretion, focus on either changes in mean circulating levels of LH or the LH surge.…”

Neural control of cyclic reproductive functions in the mammal

“…After lesioning the baso-lateral amygdala in the female deermouse, plasma LH levels increased and pituitary LH decreased (Eleftheriou and Zolovick, 1967). In a series of amygdaloid experiments on the male deermouse, Eleftheriou et al (1970) found that baso-lateral and cortical lesions also resulted in significant increase in pituitary LH (OAAD) and plasma LH (seminal vesicle and fructose test). Lesions to the medial amygdala, however, decreased LHRF, whereas baso-lateral and cortical lesions increased it.…”