Effects of an Exercise Program on Blood Biochemical Values and Exercise Stage of Chronic Kidney Disease Patients

Abstract

Background: Chronic kidney disease (CKD) patients face a relatively high risk of cardiovascular disease morbidity and mortality. A healthy lifestyle facilitated by participation in a regular exercise regimen may prevent or retard conditions commonly associated with CKD, including hypertension, hyperlipidemia, and diabetes.Purpose: This study examined the effect of a tailored exercise program on blood biochemical values and other exerciserelated variables in CKD patients.Methods: A total of 94 subjects diagnosed with CKD by a nephrology outpatient clinic at a medical center in northern Taiwan participated in this quasi-experimental study. Subjects were randomly divided into an experimental group (n = 45) or a control group (n = 49). Experimental group subjects agreed to join a 3-month exercise program. Individual guidance was given remotely to the experimental group over the telephone during the second and the third months following initiation of the exercise intervention. Both groups completed the pretest and posttest forms of the Stages of Exercise Questionnaire, and blood biochemical data were obtained from patient medical files. Data were analyzed using analysis of covariance.Results: The preexercise cholesterol values (from 198.03 T 43.52 to 160.97 T 37.39 mg/dl) of the experimental group differed significantly from their postexercise values. Also, the number of subjects in the experimental group who reported exercising regularly rose from 57.8% pretest to 75.6% posttest. However, changes in red blood cell count, hemoglobin, hematocrit, and blood sugar were all insignificant in the experimental group. No significant change in any of these items was detected in the control group. The cholesterol value of the experimental group (158.75 mg/dl) was significantly lower than that of the control group (177.29 mg/dl) after applying analysis of covariance, using the pretest results of both groups as the covariate.Conclusions and Implications for Practice: The developed exercise program was found to reduce cholesterol levels in CKD patients effectively, to encourage more patients to do exercise regularly, and to offer clinical nursing staff an approach to encourage and teach CKD patients to exercise.

Dietary Restriction and Exercise for Diabetic Patients with Chronic Kidney Disease: A Systematic Review

“…Six studies were randomized controlled trials [3] , [4] , [5] , [6] , [7] , [8] , one was a non-randomized controlled trial [9] , three were prospective uncontrolled studies [10] , [11] , [12] and one was a retrospective study [13] . The number of participants included in each study ranged from 4 [10] to 251 [6] .…”

Effect of an exercise training intervention with resistance bands on blood cell counts during chemotherapy for lung cancer: a pilot randomized controlled trial

“…Moreover, it is possible that an aerobic training component is necessary to elicit changes in RBC in cancer populations. It is also important to note that some exercise trials in other populations, such as chronic kidney patients (Chen et al 2010) and adolescents (Ulrich et al 2010) did not result in significant changes in RBCs, and that high volumes of endurance training typically result in decreases in RBCs (Mairbaurl 2013). Nonetheless, trials with larger sample sizes, different exercise modalities or means of objectively measuring exercise intensity may be needed to determine if exercise can have an effect on RBC counts in lung cancer populations.…”

Diabetic Kidney Disease: A Report From an ADA Consensus Conference

“…Dietary approaches may facilitate control of BP and management of DKD (4,20,123). Physical activity is associated with a delay in the decline of kidney function (169) and improves other risk factors in patients with CKD (170). A high BMI is a strong, potentially modifiable, risk factor for both CKD and ESRD (171).…”