Effects of antioxidant vitamins A, C, E and trace elements Cu, Se on CuZn SOD, GSH‐Px, CAT and LPO levels in chicken erythrocytes

Aydemir, T.; Öztürk, Raziye Tülümen; Bozkaya, Lütfiye Arzu; Tarhan, Leman

doi:10.1002/(sici)1099-0844(200006)18:2<109::aid-cbf861>3.3.co;2-u

Cited by 13 publications

(14 citation statements)

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“…Supplementation with antioxidative vitamins (A, C, E) and mineral micronutrients (including Cu and Se) increased the SOD activity, but did not affect the catalase activity in chicken blood and enhanced glutathione peroxidase GPx in brain tissue (Aydemir et al., 2000). In our studies, the used diets significantly affected only selected antioxidant blood parameters.…”

Section: Discussionmentioning

confidence: 99%

Antioxidation status and histidine dipeptides content in broiler blood and muscles depending on protein sources in feed

Kopeć

Jamroz

Wiliczkiewicz

et al. 2012

Animal Physiology Nutrition

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One-day-old chickens were fed mixtures containing different raw materials (fish by-products meal, porcine blood cells meal, blood meal, wheat gluten, fodder yeast), as a source of histidine and β-alanine - components of carnosine. Control birds were administered a feed mixture, in which soy bean meal was the main protein source. The bodyweight, feed consumption and conversion, antioxidant characteristics and histidine dipeptides content in blood and muscles, and also amino acid composition of chicken meat on day 34 post-hatch were recorded. The best (p < 0.05) performance and feed conversion were observed in chickens fed mixture containing porcine blood cells meal. In blood plasma of control chickens, a significantly (p < 0.01) higher ability to scavenge DPPH radicals was found. However, the highest catalase activity in erythrocytes was determined in chickens fed mixtures with blood by-products. Insignificant differences in both carnosine and anserine levels in plasma between treatments were noted. Breast muscles from control birds were characterized by lower activity of glutathione peroxidase (GPx), superoxide dismutase (SOD) and catalase (CAT) (p < 0.05; p < 0.01), than those from chickens fed blood by-products. Improved ability to reduce ferric ions (FRAP) (p < 0.01) and carnosine content in meat from chickens fed blood cell meal were recorded. No direct relations between amino acids content in feed mixtures and in meat were observed.

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Section: Discussionmentioning

confidence: 99%

Antioxidation status and histidine dipeptides content in broiler blood and muscles depending on protein sources in feed

Kopeć

Jamroz

Wiliczkiewicz

et al. 2012

Animal Physiology Nutrition

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“…These enzymes protect the cell membrane against peroxidation by converting the reactive compounds to less harmful or harmless metabolites. The determinations of MDA concentrations and antioxidant enzymes activities are the major criteria concerning the severity of possible peroxidation, which takes place in cell membrane (Aydemir et al, 2000;Gokhan et al, 2004;Ozturk-Ureket al, 2001). The decrease in activities of these antioxidant enzymes proved that lead indeed induced generation of reactive oxygen species/free radicals leading to increase production of MDA which was much higher than the level which could be compensated by the cellular defense systems, thus these compounds may not be converted to less harmful or ineffective metabolites at the sufficient levels.…”

Section: Discussionmentioning

confidence: 99%

Haematological and antioxidant enzyme response to Lead toxicity in male Wistar rats

et al. 2017

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The study evaluated the haematological and some antioxidant enzymes response to lead toxicity in male Wistar rats. Twenty male Wistar rats were divided into four groups viz., A, B, C and D. Group A served as the control while groups B, C and D were treated with 200, 300 and 400 ppm of lead (Pb) as lead acetate, respectively. Doses were orally administered in divided doses by intubation to ensure that each rat had the specified doses, after which they have access to water and feed. At the end of two weeks of treatment, blood samples were collected via the median canthus into heparinised tubes for blood lead determination and haematological analysis after which the remaining blood was centrifuged to obtain the plasma for determination of malonydialdehyde, catalase, superoxide dismutase and peroxidase levels. There was a significant increase in blood lead concentrations ranging from 2.15±0.10 µg/dl to 9.21±0.05 µg/dl which was dose dependent while decreases in packed cell volume and the red blood cell counts ranging from 32-53% and 15-52%,respectively. At the highest dose of 400 ppm of lead there was significant decrease in the neutrophils and lymphocytes. There was significant (P<0.05) dose dependent increases in malondialdehyde while the activities of catalase, peroxidase and superoxide dismutase were significantly (P<0.05) reduced. In conclusion, lead disrupts the haematological system leading to generation of free radicals that overwhelm the antioxidant enzymes thus leading to oxidative stress.

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“…Recent studies have focused on the biological variability of both antioxidant defence mechanisms and (LPO) with ageing. Animal studies have shown that antioxidant enzyme levels in chicken erythrocytes and tissues are variable depending on the availability of antioxidants in the diet (Aydemir et al., 2000; Urek et al., 2001).…”

Section: Introductionmentioning

confidence: 99%

The Effect of Kefir on the Activities of GSH‐Px, GST, CAT, GSH and LPO Levels in Carbon Tetrachloride‐Induced Mice Tissues

Güven

Gülmez

2003

Journal of Veterinary Medicine, Series B

138

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Functional foods including kefir have increasingly become as popular as before in the developing world. The health benefits of kefir including the antioxidative effects are still under evaluation. Vitamin E is also a well-known antioxidant. The biologically damaging effects of reactive oxygen species are controlled in vivo by a wide spectrum of antioxidant defence mechanisms. Dietary constituents of antioxidative vitamins and other nutrients may play an important role in protecting the body against oxidative damage. The study was carried out to investigate the protective effect of kefir against oxidative damage of CCl4 in mice, compared with the well-known antioxidant vitamin E. Three-week-old Swiss Albino mice, weighing 22-26 g were used for the experiment. At the end of the microbiological analysis of kefir, the averages of the total mesophilic aerobic colony counts, lactic acid bacteria, lactic streptococci, enterococci, and yeasts were found to be 1.04 x 10(9), 9.87 x 10(8), 4.38 x 10(8), 7.80 x 10(4) and 1.26 x 10(5) CFU/ml, respectively. While both vitamin E and kefir were found to have a protective effect against CCl4-induced damage, kefir was more protective. This may probably be the first study to compare the antioxidative action of kefir and vitamin E in the animal model.

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Effects of antioxidant vitamins A, C, E and trace elements Cu, Se on CuZn SOD, GSH‐Px, CAT and LPO levels in chicken erythrocytes

Cited by 13 publications

References 0 publications

Antioxidation status and histidine dipeptides content in broiler blood and muscles depending on protein sources in feed

Antioxidation status and histidine dipeptides content in broiler blood and muscles depending on protein sources in feed

Haematological and antioxidant enzyme response to Lead toxicity in male Wistar rats

The Effect of Kefir on the Activities of GSH‐Px, GST, CAT, GSH and LPO Levels in Carbon Tetrachloride‐Induced Mice Tissues

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