Effects of Ascophyllum nodosum extract on growth performance and immune function of young pigs challenged with Salmonella typhimurium1

Turner, John P.; Dritz, S. S.; Higgins, James J.; Minton, J. Ernest

doi:10.2527/2002.8071947x

Cited by 100 publications

(73 citation statements)

References 6 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…This is similar to the results demonstrated by Turner et al (2002) and Gardiner et al (2008), when this type of product is administered close to the weaning age, providing a longer period of time for the digestive system to improve the animals' physiological efficiency in the following production periods.…”

Section: Discussionsupporting

confidence: 77%

Supplementing nursery pig feed with seaweed extracts increases final body weight of pigs

Ruiz

Gädicke

Andrades

et al. 2018

Austral j. vet. sci.

View full text Add to dashboard Cite

ABSTRACT. Probiotics have been used as an alternative method to antibiotic treatment. In this study, we evaluated the effect of seaweed extracts, commercially named OceanFeed Swine ® (OFS), on body weight, average daily weight gain (ADG) and feed efficiency (FE) in nursery and fattening pigs of terminal lines. The study was conducted with 1809 piglets from weaning age until the end of the fattening phase on a commercial farm, divided into two groups (control and OFS; 905 and 904 pigs, respectively). Three replicates were made during the 6 weeks of production. Food was elaborated in the same productive unit and was given to the animals in the form of flour. OceanFeed Swine ® (5 g/kg of diet) was added to the diet of the OFS groups during the nursery period, from 21 to 55 days of age. The faecal microbial population was evaluated at 35 and 60 days of life. In this paper, we observed a positive effect of administering OceanFeed Swine ® on the production parameters analysed in the fattening phase, showing an improvement of 26 g in ADG and FE of 0.07. It can be concluded that the use of OceanFeed Swine ® in the diets of the piglets, aged between 21 to 55 days old, improves FE (Control 2.36, OFS 2.29) and ADG (control 0.798 kg, OFS 0.824 kg). Moreover, its use exhibited an increase in the slaughter weight, a reduction of E coli CFU, and an increase in Lactobacillus sp. in fattening animals. All these improvements have a major positive economic impact per pig at time of slaughter.

show abstract

Section: Discussionsupporting

confidence: 77%

Supplementing nursery pig feed with seaweed extracts increases final body weight of pigs

Ruiz

Gädicke

Andrades

et al. 2018

Austral j. vet. sci.

View full text Add to dashboard Cite

show abstract

“…However, it can be attributed to the increased feed intake of pigs supplemented with the laminarin and fucoidan extract. Increased feed intake was also reported in previous pig-feeding studies (Allen et al, 2001;Turner et al, 2002) to seaweed extract supplementation. Pluske et al (1996) demonstrated that villus height and crypt height could be maintained if piglets do not suffer the nutritional stress associated with interrupted feed intake immediately post weaning.…”

Section: Discussionmentioning

confidence: 48%

“…The use of seaweed extracts in pig diets has given variable responses (Allen et al, 2001;Turner et al, 2002;Gardiner et al, 2008). Gardiner et al (2008) reported linear decreases in daily gain as the level of an Ascophyllum nodosum extract increased in healthy grower-finisher pigs.…”

Section: Discussionmentioning

confidence: 99%

Performance of weanling piglets offered low-, medium- or high-lactose diets supplemented with a seaweed extract from Laminaria spp.

Gahan¹,

Lynch²,

Callan³

et al. 2009

Animal

View full text Add to dashboard Cite

An experiment (3 3 4 factorial arrangement) was conducted to investigate the interaction between different levels of lactose (60 v. 150 v. 250 g/kg) and seaweed extract (0 v. 1 v. 2 v. 4 g/kg) containing both laminarin and fucoidan derived from Laminaria spp. on growth performance and nutrient digestibility of weanling pigs. In all, 384 piglets (24 days of age, 7.5 kg (s.d. 1 kg) live weight) were blocked on the basis of live weight and were assigned to one of 12 dietary treatments (eight replicates per treatment). Piglets were offered diets containing either low (60 g/kg), medium (150 g/kg) or high (250 g/kg) lactose levels with one of the following levels of seaweed extract additive: (1) 0 g/kg, (2) 1 g/kg, (3) 2 g/kg or (4) 4 g/kg seaweed extract. The pigs were offered the diets ad libitum for 21 days post weaning. There was a significant lactose 3 seaweed extract interaction (P , 0.05) in average daily gain (ADG) during the experimental period (days 0 to 21). At the low and medium levels of lactose, there was an increase in ADG as the level of seaweed extract increased to 2 g/kg (P , 0.05). However, at the high level of lactose there was no further response in ADG as the level of seaweed extract increased above 1 g/kg. There was a significant lactose 3 seaweed extract interaction during the experimental period (days 0 to 21) (P , 0.05) on the food conversion ratio (FCR). At the low level of lactose, there was a significant improvement in FCR as the levels of seaweed extract increased to 4 g/kg (P , 0.01). At the medium level of lactose, there was a significant improvement in FCR as seaweed extract increased to 2 g/kg. However, there was no significant effect of seaweed extract on FCR at the high levels of lactose (P . 0.05). There was a linear increase in average daily feed intake (ADFI) during the experimental period (days 0 to 21) (P , 0.05) as levels of seaweed extract increased. There was a linear increase in ash digestibility (P , 0.01) during the experimental period (days 0 to 21) as the level of lactose increased. There was a quadratic decrease (P , 0.01) in nitrogen (N) and neutral detergent fibre digestibility as the levels of lactose increased. In conclusion, pigs responded differently to the inclusion levels of seaweed extract at each level of lactose supplementation. The inclusion of a laminarin-fucoidan extract in piglet diets may alleviate the use for high-lactose diets (.60 g/kg) and would also alleviate some of the common problems that occur post weaning.

show abstract

“…In vitro, a dose of 10 mg/ml of A. nodosum (greatly exceeding the highest level of feed incorporation level of 2%) was able to activate porcine alveolar macrophages to secrete prostaglandin E2. However, this dose did not alter the secretion of IL-10 by splenocytes (Turner et al, 2002a). Taken together, the in vitro and in vivo data suggest that A. nodosum extract probably has only little direct effect on gut immune system in pig.…”

Section: In-feed Modulators Of Piglet Immunitymentioning

confidence: 67%

“…To date, we are only aware of one study that presents data on influence of a seaweed extract on the immune parameters in pig production. This extract was derived from Ascophyllum nodosum, and different levels of incorporation ranging from 0% to 2% were tested in piglets orally challenged with 6 3 10 9 CFU (colony forming units) of Salmonella enterica serovar Typhimurium (Turner et al, 2002a). Increasing levels of A. nodosum tended to linearly enhance the feed intake, but decreased the feed efficiency during the 4 weeks following the weaning of piglets.…”

Section: In-feed Modulators Of Piglet Immunitymentioning

confidence: 99%

Natural alternatives to in-feed antibiotics in pig production: can immunomodulators play a role?

Gallois¹,

Rothkötter

Bailey

et al. 2009

Animal

View full text Add to dashboard Cite

As a result of the European ban of in-feed growth-promoting antibiotics, new strategies are being developed to increase the resistance to disease in farm animals. In pig production, this is of particular importance during the weaning transition when piglets are subjected to major stressful events, making them highly sensitive to digestive disorders. At this time, the development of both innate and adaptive immunity at the mucosal surface is critical in preventing the potential harmful effects of intestinal pathogenic agents. Strategies aiming at stimulating natural host defences through the use of substances able to modulate immune functions have gained increasing interest in animal research, and different bioactive components a priori sharing those properties have been the subject of in vivo nutritional investigations in pig. Among these, yeast derivates (b-glucans and mannans) are able to interact with immune cells, particularly phagocytic cells. However, studies where they have been fed to pigs have shown inconsistent results, suggesting that their ability to target the sensitive immune cells through the oral route is questionable. The plant extracts, which would benefit from a positive image in the public opinion, have also been tested. However, due to a lack of data on the bioactive components of particular plants and the large diversity of species, it has proved difficult to prepare extracts of equivalent potency and thus, the literature on their influence on pig immunity remains inconclusive. In considering piglet immunity and health benefits, the most promising results to date have been obtained with spray-dried animal plasma, whose positive effects would be provided by specific antibodies and nonspecific competition of some plasma components with bacteria for intestinal receptors. The major positive effect of spray-dried animal plasma is in reducing the infiltration of gut-associated lymphoid tissue by immune cells, which is likely to be the result of a decreased colonisation by potentially harmful bacteria. This review also highlights the limitations of some of the published in vivo studies on the immunomodulatory activity of certain feed additives. Among those, the lack of standardisation of extracts and the heterogeneity of piglet-rearing conditions (e.g. exposure to pathogens) are likely the most limiting.

show abstract

Effects of Ascophyllum nodosum extract on growth performance and immune function of young pigs challenged with Salmonella typhimurium1

Cited by 100 publications

References 6 publications

Supplementing nursery pig feed with seaweed extracts increases final body weight of pigs

Supplementing nursery pig feed with seaweed extracts increases final body weight of pigs

Performance of weanling piglets offered low-, medium- or high-lactose diets supplemented with a seaweed extract from Laminaria spp.

Natural alternatives to in-feed antibiotics in pig production: can immunomodulators play a role?

Contact Info

Product

Resources

About