Effects of Baduanjin exercise for knee osteoarthritis: A systematic review and meta-analysis

Zeng, Zhipeng; Liu, Ya-Bin; Fang, Jinju; Liu, Yue; Luo, Jun; Yang, Meng

doi:10.1016/j.ctim.2019.102279

Cited by 58 publications

(61 citation statements)

References 38 publications

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“…As a low-impact aerobic exercise with soft movements, Baduanjin could stretch and relax musculoskeletal throughout the entire body [16]. Previous studies have reported that Baduanjin can improve fatigue, balance and physical flexibility in older peoples [14,16]. Importantly, partial Baduanjin poses [14,31,32] could especially enhance the strengthen of lower limb muscles.…”

Section: Discussionmentioning

confidence: 99%

“…Previous studies have reported that Baduanjin can improve fatigue, balance and physical flexibility in older peoples [14,16]. Importantly, partial Baduanjin poses [14,31,32] could especially enhance the strengthen of lower limb muscles. For example, "drawing the bow on both sides" contracts the hamstring muscles and stretches the quadriceps; "swaying the head and shaking the tail" exercises the adductor and abductor muscles of lower limbs; "bouncing on the toes" enhances the strength of the anterior and posterior muscles of the lower limbs at the same time by putting knees together and lifting heels.…”

Section: Discussionmentioning

confidence: 99%

“…Baduanjin qigong: The entire set of Baduanjin exercises in this study, recommended by Chinese Health Qigong Association in 2003, consisted of eight postures [14]. It was recommended to practice Baduanjin one time a day, two sets each time [14,15]. It takes about 20 minutes to complete a full set of Baduanjin.…”

Section: Quadriceps Strengthening Exercises (Qse)mentioning

confidence: 99%

“…In the management of KOA, Tai Chi is recommended as one of the most appropriate exercise interventions [9]. Baduanjin, as one of well-known traditional Chinese Qigong, is similar to Tai Chi but requires fewer movements and shorter durations [14]. Studies show that Baduanjin has physiological and psychological effects on patients with various diseases, for example, it reduced the symptoms of morning stiffness, spinal pain and fatigue for patients with ankylosing spondylitis [15], alleviated musculoskeletal pain in older people with chronic low back pain and neck pain [16,17].…”

Section: Introductionmentioning

confidence: 99%

“…Studies show that Baduanjin has physiological and psychological effects on patients with various diseases, for example, it reduced the symptoms of morning stiffness, spinal pain and fatigue for patients with ankylosing spondylitis [15], alleviated musculoskeletal pain in older people with chronic low back pain and neck pain [16,17]. and improved mental conditions for a variety of participants [18].A recent review evaluating the effectiveness and safety of Baduanjin for KOA identified only three randomized controlled trials [14]. Results from this review revealed that Baduanjin is a simple and suitable aerobic exercise for elderly people with KOA, while the effect of Baduanjin on improving OA symptoms needs further investigation.…”

Section: Introductionmentioning

confidence: 99%

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Effect of quadriceps strengthening exercises alone and in combination with Baduanjin qigong on older adults with knee osteoarthritis: a quasi-experimental study

wang

Zhang

Tong

et al. 2020

Preprint

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BackgroundExercise is recommended as a core treatment for individuals with KOA. However, the optimal exercise program to promote long-term compliance for KOA patients is not clear. The aim of this study is to compare the effects of the combination exercise program (quadriceps strengthening exercises (QSE) plus Baduanjin qigong) versus QSE alone on older adults with knee osteoarthritis (KOA). MethodsA two-arm, quasi-experimental trial with repeated measurements was used. As a cluster randomized trial, participants from one community center were assigned to combination exercise group while participants from the other center were assigned to QSE group. We assessed pain intensity, physical function, self-efficacy, and HRQoL with standardized instruments at baseline, 3 and 6 months. Results87 participants with KOA who aged above 60 completed the study. Over the 6 months, There were significant time by group interaction effects on pain intensity (F = 44.419, p < 0.001), physical function (F = 46.904, p < 0.001) and self-efficacy (F = 49.754, p < 0.001), as well as in the physical component summary (F = 15.205, p < 0.001) and mental component summary of SF-12 (F = 19.205, p < 0.001), with the combination exercise group exhibiting significantly greater improvements in all outcomes than QSE group. ConclusionsCombination exercise treatment is more effective than QSE for relieving pain, increasing physical functioning, and improving self-efficacy, and quality of life in community-dwelling KOA older adults. Also, it could promote long-term compliance for KOA community patients.Trial registrationChinese Clinical Trails Registry number ChiCTR2000033387 (retrospectively registered). Registered 30 May 2020

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Quadriceps Strengthening Exercises (Qse)mentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Effect of quadriceps strengthening exercises alone and in combination with Baduanjin qigong on older adults with knee osteoarthritis: a quasi-experimental study

wang

Zhang

Tong

et al. 2020

Preprint

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LINC02288 promotes chondrocyte apoptosis and inflammation through miR‐374a‐3p targeting RTN3

Zhu

Wang

et al. 2021

The Journal of Gene Medicine

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Background: Dysregulation of long non-coding RNAs (lncRNAs) is related to the occurrence of osteoarthritis (OA). In the present study, we explored the role of LINC02288 and its regulatory mechanism in OA development.Methods: GSE113825 was obtained from Gene Expression Omnibus (GEO) database and analyzed to identify the differentially expressed lncRNAs in OA. Gene enrichment analyses and Kyoto Encyclopedia of Genes and Genomes biological process analysis were performed through Metascape (http://metascape.org/gp). The interactions among LINC02288, miR-374a-3p and RTN3 were determined using RNA immunoprecipitation (RIP) assays and dual luciferase reporter assays. Chondrocyte apoptosis was examined using flow cytometry. Western blot assays were conducted to assess the pro-apoptotic and anti-apoptotic markers.Results: We identified a total of 4,491 differentially expressed lncRNAs. We focused on LINC02288 as the top-ranked up-regulated lncRNA in OA as indicated by a significant p-value. LINC02288 was significantly up-regulated, which was further verified by a real-time polymerase chain reaction. Down-regulation of LINC02288 significantly reduced the apoptosis of OA chondrocytes induced by interleukin-1β and the production of pro-inflammatory cytokines. These effects were further verified in an OA rat model. An RIP assay and dual luciferase assay further confirmed that LINC02288 served as a sponge of miR-374a-3p. Moreover, the overexpression of RTN3 could partially reverse the effects of LINC02288 knockdown, mediating inhibitory effects on chondrocyte apoptosis and the inflammatory response. Down-regulation of LINC02288 alleviated OA development in an in vivo OA animal model. Conclusions:Our findings indicate that LINC02288 contributes to OA progression by targeting the miR-374a-3p/RTN3 axis, which might provide a promising molecular therapy strategy for OA.

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Concept for integrative pain treatment of osteoarthritis of the knee based on the evidence for conservative and complementary therapies

Irnich,

Bäumler

2023

Schmerz

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Effects of Baduanjin exercise for knee osteoarthritis: A systematic review and meta-analysis

Cited by 58 publications

References 38 publications

Effect of quadriceps strengthening exercises alone and in combination with Baduanjin qigong on older adults with knee osteoarthritis: a quasi-experimental study

Effect of quadriceps strengthening exercises alone and in combination with Baduanjin qigong on older adults with knee osteoarthritis: a quasi-experimental study

LINC02288 promotes chondrocyte apoptosis and inflammation through miR‐374a‐3p targeting RTN3

Concept for integrative pain treatment of osteoarthritis of the knee based on the evidence for conservative and complementary therapies

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