Effects of "Bioactive" amino acids leucine, glutamate, arginine and tryptophan on feed intake and mRNA expression of relative neuropeptides in broiler chicks

Wang, Songbo; Khondowe, Paul; Yu, Jianjian; Shu, Gang; Zhu, Xiaotong; Wang, Lina; Gao, Ping; Xi, Qianyun; Zhang, Yongliang; Jiang, Qingyan

doi:10.1186/2049-1891-3-27

Cited by 16 publications

(5 citation statements)

References 41 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Wang et al (2012) also reported that administration of L-glutamate (1.6 μmol) decreased feed intake and increased hypothalamic CRF and MC4R mRNA expression levels. However, in those studies, the AA were injected directly in the central nervous system (ICV), and therefore, further studies to evaluate the influence of glutamine and glutamate on broiler feed intake are needed.…”

Section: Resultsmentioning

confidence: 99%

Effects of Dietary L-Glutamine or L-Glutamine Plus L-Glutamic Acid Supplementation Programs on the Performance and Breast Meat Yield Uniformity of 42-d-Old Broilers

Jr¹,

Albino

Rostagno

et al. 2015

Rev. Bras. Cienc. Avic.

View full text Add to dashboard Cite

This study aimed at evaluating four dietary L-Glutamine (L-Gln) or L-Gln plus L-Glutamate (L-Glu) supplementation programs on the performance, breast yield, and uniformity of broilers. A total of 2,112 one-d-old male Cobb 500 ® broilers were distributed according to a randomized block design in a 2 × 4 factorial arrangement (L-Gln or L-Gln plus L-Glu × 4 supplementation programs), totaling eight treatments with 12 replicates of 22 broilers each. The supplementation programs consisted of the dietary inclusion or not of 0.4% of L-Gln or L-Gln plus L-Glu for four different periods: 0 days (negative control), 9d, 21d, and 42d. Feed intake (FI, g), body weight gain (BWG, g), feed conversion ratio (FCR, kg/kg), coefficient of variation of body weight (CV, %), body weight uniformity (UNIF, %), breast weight (BW, g), breast yield (BY, %), coefficient of variation of breast weight (CV B ), breast uniformity (UNIF B ), coefficient of variation of breast yield (CV BY ), and breast yield uniformity (UNIF BY ) were evaluated. Birds fed the diets treatments supplemented with L-Gln or L-Gln plus L-Glu for 9d presented 3% higher BWG (p<0.05) compared with the controls. The L-Gln or L-Gln plus L-Glu supplementation until broilers were 21 days old resulted in 14, 10, 16, and 12% improvements (p<0.05) in CV, UNIF, CV BY , UNIF BY , respectively. The supplementation of 0.4% L-Gln (L-Gln 99%) or L-Gln plus L-Glu (minimum 95%) to pre-starter and starter broiler diets is recommended to improve body weight gain and uniformity.

show abstract

Section: Resultsmentioning

confidence: 99%

Effects of Dietary L-Glutamine or L-Glutamine Plus L-Glutamic Acid Supplementation Programs on the Performance and Breast Meat Yield Uniformity of 42-d-Old Broilers

Jr¹,

Albino

Rostagno

et al. 2015

Rev. Bras. Cienc. Avic.

View full text Add to dashboard Cite

show abstract

“…Although the feed efficiency in some birds, such as turkeys, is not affected by dietary supplementation with Trp, other poultry and mammals show obvious changes in feed intake after Trp supplementation (Denbow et al, 1993;Corzo et al, 2005;Wang et al, 2012). This improvement in growth performance was largely attributed to the enhanced appetite and increased feed intake induced by Trp and/or its metabolites.…”

Section: Discussionmentioning

confidence: 99%

Effects of Dietary Tryptophan on Growth Performance, Plasma Parameters, and Internal Organs of 1–28-Day-Old Sichuan White Geese

Liu

et al. 2023

J. Poult. Sci.

View full text Add to dashboard Cite

Although the nutrient requirements of geese during the growing stage are known, the dietary requirement of amino acids during the starting period remains unclear. Optimum nutrient supplementation during the starting period is crucial for improved survival rates, body-weight gain, and marketing weight in geese. Our study focused on the effect of dietary tryptophan (Trp) supplementation on the growth performance, plasma parameters, and internal-organ relative weights in 1-28-day-old Sichuan white geese. A total of 1080 1-day-old geese were divided randomly into six Trp-supplemented (0.145%, 0.190%, 0.235%, 0.280%, 0.325%, and 0.370%) groups. Average daily feed intake (ADFI), average daily gain (ADG), and duodenal relative weight were highest in the 0.190% group, brisket protein level and jejunal relative weight in the 0.235% group, and plasma total protein and albumin levels in the 0.325% group (P < 0.05). Dietary Trp supplementation did not significantly affect the relative weights of the spleen, thymus, liver, bursa of Fabricius, kidneys, and pancreas. Moreover, the 0.145% -0.235% groups showed significantly decreased liver fat (P < 0.05). Based on the non-linear regression analysis of ADG and ADFI, the dietary Trp levels between 0.183% and 0.190% were estimated to be optimal for 1-28-day-old Sichuan white geese. In conclusion, optimal dietary Trp supplementation in 1-28-day-old Sichuan white geese resulted in increased growth performance (0.180% -0.190%) along with improved proximal intestinal development and brisket protein deposition (0.235%). Our findings provide basic evidence and guidance for optimal levels of Trp supplementation in geese.

show abstract

“…##, ••, and **p < .01; *p < .05, compared with the controls of the area with the same color and is used to improve food flavor (Zeb & Rahman, 2017). Leucine is a branched-chain amino acid, known to enhance the appetite and prevent muscle injury (Wang et al, 2012). Therefore, these two amino acids may confer important biological activities to AMB.…”

Section: Discussionmentioning

confidence: 99%

Antioxidant activity of organic sulfides from fresh Allium macrostemon Bunge and their protective effects against oxidative stress in Caenorhabditis elegans

Ma³

et al. 2020

J. Food Biochem.

View full text Add to dashboard Cite

Long-stamen chive (Allium macrostemon Bunge; AMB), which is prevalent in the Wuling Mountain area of China, is a characteristic food of the nation. In the study, we evaluated the as-yet-unknown nutritional value and antioxidant activity of fresh AMB. The free amino acid content, volatile components, and free radical-scavenging capacity of isolated organic sulfides were analyzed to evaluate the qualitative and physiological properties of fresh AMB. The plant was found to be rich in free essential amino acids and contain multiple flavor-imparting amino acids. The organic sulfides showed an apparent free radical-scavenging activity in vitro. Furthermore, these sulfides alleviated oxidative stress in Caenorhabditis elegans. Notably, the organic sulfides isolated from AMB enhanced the activities of superoxide dismutase, catalase, and glutathione peroxidase; improved motility; and extended the lifespan in oxidative stress-affected nematodes. In conclusion, our study indicates that AMB is a nutritious vegetable with potential to be developed as a functional food. Practical applications Long-stamen chive is a wild edible vegetable belonging to the genus Allium (A. macrostemon Bunge; AMB). However, its quality and physiological properties have not been comprehensively investigated. Herein, we analyzed the free amino acid content, composition of volatile compounds, and potential antioxidative properties of AMB. Our results indicated that AMB is rich in essential amino acids, making it a highly nutritious food. Further analysis indicated that AMB contains a high proportion of organic sulfides, which have been previously been shown to have antioxidative properties. Together, our findings indicate that AMB contains important bioactive components and can be developed as a functional food or health supplement. Furthermore, our findings will enhance public awareness regarding this wild resource and provide new directions for the research and development of natural products derived from it.

show abstract

Effects of "Bioactive" amino acids leucine, glutamate, arginine and tryptophan on feed intake and mRNA expression of relative neuropeptides in broiler chicks

Cited by 16 publications

References 41 publications

Effects of Dietary L-Glutamine or L-Glutamine Plus L-Glutamic Acid Supplementation Programs on the Performance and Breast Meat Yield Uniformity of 42-d-Old Broilers

Effects of Dietary L-Glutamine or L-Glutamine Plus L-Glutamic Acid Supplementation Programs on the Performance and Breast Meat Yield Uniformity of 42-d-Old Broilers

Effects of Dietary Tryptophan on Growth Performance, Plasma Parameters, and Internal Organs of 1–28-Day-Old Sichuan White Geese

Antioxidant activity of organic sulfides from fresh Allium macrostemon Bunge and their protective effects against oxidative stress in Caenorhabditis elegans

Contact Info

Product

Resources

About