2020
DOI: 10.20944/preprints202010.0080.v1
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Effects of Bioflavonoids from Taxus Media var. Hicksii on Superoxide Generation, Phosphorylation of Proteins and Translocation of Cytosolic Compounds to the Cell Membrane in Human Neutrophils

Abstract: In present work, the effects of bioflavonoids (ginkgetin and sciadopitysin) on stimulus-induced superoxide generation, tyrosyl and serine/threonine phosphorylation of proteins in human neutrophils, and the translocation of cytosolic compounds (p47phox, p67phox and Rac) to cell membrane were studied, which were isolated from the needles of Taxus media var. Hicksii. Meanwhile, three normal flavonoids (apigenin, quercetin and isoquercetin) were involved as contrasts. The results indicated that ginkgetin and sciad… Show more

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