Effects of camel milk in dyslipidaemia: A randomised clinical trial

Mohammaddin, Asma; Rohra, Dileep Kumar; Mortaja, Sarah; Abanmi, Shahad; Saati, Ola Al; Cahusac, Peter; Khawaja, Rajab Ali; Al-Selaihem, Ahmad; Al-Omran, Yousef

doi:10.1016/j.idairyj.2018.03.015

Cited by 9 publications

(4 citation statements)

References 40 publications

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“…Camel is a domesticated animal, which is an important resource of food in many countries of the world including the Middle East. The health benefits of camel milk are associated with its antimicrobial (Abdel‐Hamid et al., 2016), dislipedemic (Mohammaddin et al., 2018), antidiabetic (Fallah et al., 2020), and anticancer (Abrhaley & Leta, 2018) properties, and its richness of minerals and vitamins (Swelum et al., 2021).…”

Section: Introductionmentioning

confidence: 99%

Detection of multimycotoxins in camel feed and milk samples and their comparison with the levels in cow milk

Zeidan

Hassan

Al‐Naimi

et al. 2021

Food Science & Nutrition

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Camel milk has been considered as an important source of nutrients and is commercialized in many countries of the world including the Middle East. This study aimed to investigate the presence of mycotoxins in camel feed and milk samples in comparison with the cow milk. Fumonisins (FUM), ochratoxin A (OTA), and zearalenone (ZEN) were detected in 14%, 39%, and 39% of the tested camel feed samples, respectively. Among the tested camel feed samples, 8.3% and 5.6% were co‐contaminated with OTA+FUM and FUM+ZEN, respectively. In the case of milk samples, 46.15% of camel and 63.63% of cow were found contaminated with aflatoxin M1 (AFM1). In total, 16.2% and 8.1% of the milk samples were simultaneously contaminated with two and three mycotoxins, respectively. Although the levels of individual mycotoxins in the camel feed and milk samples were within the European Union (EU) permissible limits, their co‐occurrence may pose severe risk to human and animal health due to possible additive and/or synergistic toxicities.

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Section: Introductionmentioning

confidence: 99%

Detection of multimycotoxins in camel feed and milk samples and their comparison with the levels in cow milk

Zeidan

Hassan

Al‐Naimi

et al. 2021

Food Science & Nutrition

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“…The statistical likelihood approach [25, 26] was used to determine whether the weight of evidence supported an effect of hyaluronidase against the null hypothesis of no effect. Briefly, for each comparison, this involved calculating the likelihood ratio (LR) using the profile likelihood for a t distribution [27]. The natural logarithm of the LR, called the support, provided a linear scale of evidence.…”

Section: Methodsmentioning

confidence: 99%

Does Hyaluronidase Enhance Drug Penetration to Mechanoreceptors?

Cahusac

Senok

2020

Skin Pharmacol Physiol

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Background: The pharmacological study of mechanoreceptors embedded within tissue is hampered by tissue barriers to applied research drugs. Methods: Hyaluronidase increases the permeability of tissues and is used clinically to facilitate the distribution of injected drugs. An in vitro rat sinus hair preparation was used to determine whether hyaluronidase (1,500 or 3,000 IU/10 mL) had an effect on drug access to receptor sites on slowly adapting St I and St II mechanoreceptors. Electrical recordings were made from single mechanoreceptor units that were activated by trapezoid ramp stimuli. Cinnamaldehyde (500–1,500 μM) and capsazepine (100 μM) were used as test drugs. Changes in onset time and degree of depression of firing due to test drugs were compared to control experiments not employing hyaluronidase. Results: There were no statistical effects on any of the observed measures. Often the effects were opposite to those predicted. Using a likelihood approach, it was calculated that there was strong evidence (log-likelihood ratios from −0.5 to −6.5) to support a null effect over a facilitatory effect. There was no evidence of loss of integrity of mechanoreceptor mechanotransduction mechanisms following hyaluronidase applications. Comparison with Existing Method: The use of hyaluronidase does not facilitate drug access to receptors. Conclusions: In the in vitro sinus hair preparation, the addition of hyaluronidase does not allow easier access to slowly adapting mechanoreceptors within the follicle.

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“…Bene t properties of camel milk been reported in several studies. It consist of antidiabetic (5,6), antihyperlipidemia (5,7), improvement of autistic behavior (8,9) and many other reports (10)(11)(12). There is some evidence that camel milk has anti-in ammatory effects (13)(14)(15).…”

Section: -Compliance Of Chemical Medications Are Lower In Children Comentioning

confidence: 98%

Camel milk in asthmatic children: a double blind randomized clinical trial

Bakhtiari¹,

Nekouhi²,

Zibaee³

et al. 2021

Preprint

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Asthma is one of the prevalent diseases in children. There is some evidence regarding benefits of camel milk in asthma. Present study was carried out evaluating the effect of camel milk in asthmatic children. A randomized double blind clinical trial was operated between 2018 and 2019 in a tertiary center. Sixty children aged more than 6 years with not well control asthma were included. Intervention was consist of 200 milliliter camel milk or placebo daily for 2 months. Spirometry parameters and medication regimen were assessed before and after intervention. Data was analyzed using SPSS software. A total of 57 patients completed the trial. Patients were similar in demographic and baseline characteristics (p > 0.05). There was a significant difference between groups after intervention in use of inhaled corticosteroids (96.7% versus 70.4%, p value = 0.01), short acting beta agonists (53.3% versus 29.6%, p value = 0.0001) and long acting beta agonists (53.3% versus 40.7%, p value = 0.04) in control and intervention respectively. The percent of changes in forced expiratory volume (FEV1) in control and intervention groups was 18.54 ± 14.89 and 21.89 ± 17.83 respectively (p = 0.14). The percent of changes in FEV1/forced vital capacity (FVC) in control and intervention groups was 8.11 ± 7.12 and 11.11 ± 8.33 respectively (p = 0.14). Conclusion: Camel milk leads to significant decrease in inhaled corticosteroids, short acting beta agonists and long acting beta agonist's use, surprisingly. It was suggested that camel milk is added to pharmacological treatment of asthmatic children after more studies.

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Effects of camel milk in dyslipidaemia: A randomised clinical trial

Cited by 9 publications

References 40 publications

Detection of multimycotoxins in camel feed and milk samples and their comparison with the levels in cow milk

Detection of multimycotoxins in camel feed and milk samples and their comparison with the levels in cow milk

Does Hyaluronidase Enhance Drug Penetration to Mechanoreceptors?

Camel milk in asthmatic children: a double blind randomized clinical trial

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