Effects of Carbachol and Acetylcholine on Intraocular Pressure After Cataract Extraction

IOP Elevation After Cataract Surgery: Results for Residents and Senior Staff at Henry Ford Health System

“…12,[25][26][27] In addition, the use of intracameral carbachol and acetylcholine after completion of cataract surgery has also proven useful in controlling early postoperative IOP elevation. 28,29 The results of our study suggest that the use of these agents might be advisable in resident-performed surgeries, especially those with risk factors associated with a high likelihood of significant IOP elevation acutely after cataract surgery.…”

Effect of antiglaucoma agents on postoperative intraocular pressure after cataract surgery with Viscoat

“…Its effect on postoperative IOP after phacoemulsification is well documented, 7,8 and it has been shown to induce greater increases in IOP than other OVDs. 7,[9][10][11] Various ocular hypotensive agents [12][13][14][15][16] and intracameral cholinergic agents 17,18 have been used to prevent IOP increases after phacoemulsification surgery in which various OVDs are used. However, only 1 study evaluated IOP changes after phacoemulsification surgery using only Viscoat.…”

“…However, only 1 study evaluated IOP changes after phacoemulsification surgery using only Viscoat. 17 Because no research exists on the effect of various ocular hypotensive agents on IOP increases after phacoemulsification using only Viscoat, we evaluated the effect of brinzolamide 1% (Azopt), brimonidine 0.2% (Alphagan), acetazolamide 250 mg (Diazomid), intracameral acetylcholine (Miostat), and timolol maleate 0.5% (Timoptic) on ocular hypertension in the early postoperative period after phacoemulsification performed using Viscoat.…”

Timolol 0.1% Gel versus Timolol 0.5% Eyedrops in the Prophylaxis of Ocular Hypertension after Phacoemulsification Surgery

“…A number of drugs have been investigated as possible means of controlling IOP spikes after cataract surgery but, although some of these may reduce the early postoperative increase in IOP, most have a number of limitations (10-15). Fry (16) compared the effects of the most widely used drugs (levobunolol, betaxolol, timolol, apraclonidine, acetazolamide, pilocarpine gel, and carbachol), and found that intracameral carbachol was the most effective, followed by timolol maleate.…”

“…Attempts have been made to prevent the postoperative increase in IOP using various drugs, including brinzolamide, brimonidine, acetazolamide, intracameral acetylcholine, timolol 0.5% eyedrops, timolol 0.1% gel, and a combination of timolol and dorzolamide (10-16). However, although some of these are effective in reducing the increase immediately after small-incision cataract surgery, there are no guidelines for preventing it.…”